Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   NWE22_RS00315 Genome accession   NZ_CP102747
Coordinates   54419..55771 (+) Length   450 a.a.
NCBI ID   WP_277745485.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 49419..60771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS00305 (NWE22_00305) - 50488..51756 (+) 1269 WP_174846490.1 MerR family transcriptional regulator -
  NWE22_RS00310 (NWE22_00310) comA 52254..54407 (+) 2154 WP_277745484.1 peptide cleavage/export ABC transporter ComA Regulator
  NWE22_RS00315 (NWE22_00315) comB 54419..55771 (+) 1353 WP_277745485.1 bacteriocin secretion accessory protein Regulator
  NWE22_RS00320 (NWE22_00320) - 56160..56339 (+) 180 WP_024392853.1 hypothetical protein -
  NWE22_RS00325 (NWE22_00325) - 56340..56540 (+) 201 WP_277745486.1 hypothetical protein -
  NWE22_RS00330 (NWE22_00330) - 56557..56748 (+) 192 WP_024392851.1 hypothetical protein -
  NWE22_RS00335 (NWE22_00335) - 57109..57978 (-) 870 WP_130555553.1 cysteine ABC transporter substrate-binding protein -
  NWE22_RS00340 (NWE22_00340) - 57991..58737 (-) 747 WP_277745487.1 amino acid ABC transporter ATP-binding protein -
  NWE22_RS00345 (NWE22_00345) - 58742..59419 (-) 678 WP_024392848.1 amino acid ABC transporter permease -
  NWE22_RS00350 (NWE22_00350) - 59400..60059 (-) 660 WP_239604822.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 50741.41 Da        Isoelectric Point: 4.8814

>NTDB_id=718671 NWE22_RS00315 WP_277745485.1 54419..55771(+) (comB) [Streptococcus parasuis strain SFJ45]
MDHHLLESAEFYNRRYHNAASRVIIPSCVLFLFLILFSIVAKKEMTISTRATVEPVQRLAQIHSISNHQILRNHLFENQE
ISVGDLLVEYQSENEQIQEDKIKENIAVLKNQISQLNVLKKSLESGSNQFEKEDQYGYSQMFKDYCNQLETLASTIDQQN
ATIASQNQAAKQSQLELDKVMHQTEKALADYRELKWAIQSDGVIDEENVGYSIYAQYQVAQSEDAVASQESFIAQIDNQI
SQVETQLASYKLQYASAGVQQSYTNSLDSQSASLKAQYLTKVGQEMTLLSSQLRELEATLTVQKQAMGKTKIIADQAGVV
HLNTEVEGSMMIPEGTIIAYVYPVLMEAKKMKITAYIPSKDIASISLKDNIQFSIQGKGVKRLALQSNISEIASTAIQTE
AGNFFKVEAETRISTEMAEQLRYGMEGQFVVITGKKTYFQYFIDEFLGKE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=718671 NWE22_RS00315 WP_277745485.1 54419..55771(+) (comB) [Streptococcus parasuis strain SFJ45]
ATGGACCATCATCTGTTAGAAAGTGCAGAATTTTACAACAGACGTTATCATAATGCAGCCAGTAGAGTGATTATTCCTAG
TTGTGTATTGTTTTTGTTTCTCATTCTTTTTTCAATCGTTGCAAAAAAAGAAATGACCATTTCAACAAGAGCAACAGTAG
AACCTGTACAACGATTAGCACAGATTCACTCAATCAGTAATCATCAGATTCTTAGGAATCATTTATTCGAAAATCAAGAG
ATTTCAGTTGGAGATTTATTGGTAGAATATCAATCAGAGAATGAGCAAATCCAAGAAGACAAGATCAAAGAAAACATAGC
TGTTTTGAAAAATCAGATTTCTCAACTCAATGTCTTGAAGAAAAGTTTAGAATCGGGAAGTAATCAATTTGAGAAAGAAG
ATCAATATGGTTATTCTCAAATGTTTAAGGATTATTGCAATCAATTAGAAACATTGGCAAGTACGATTGACCAACAAAAT
GCAACGATTGCATCTCAAAATCAAGCTGCAAAACAATCACAATTGGAATTGGATAAAGTAATGCATCAAACGGAGAAAGC
CTTAGCAGACTATAGAGAATTGAAATGGGCCATTCAGTCTGATGGTGTCATTGATGAGGAGAATGTTGGCTATTCAATCT
ATGCACAGTATCAGGTAGCACAATCAGAGGATGCAGTTGCCAGTCAAGAATCATTCATCGCTCAAATCGATAATCAAATC
AGTCAAGTAGAGACTCAACTGGCCAGTTATAAATTGCAATATGCCAGTGCAGGAGTGCAACAATCGTATACGAATAGCTT
GGATAGTCAGTCGGCATCGTTGAAAGCTCAATATTTAACCAAGGTTGGTCAGGAAATGACCTTGTTGTCTTCTCAATTAA
GAGAACTAGAAGCGACACTTACGGTTCAAAAACAAGCAATGGGTAAGACAAAAATTATTGCTGATCAGGCAGGGGTCGTT
CATTTAAATACAGAAGTTGAGGGCTCAATGATGATTCCAGAAGGAACAATTATTGCATATGTTTATCCAGTTCTAATGGA
AGCTAAGAAAATGAAGATTACAGCATATATTCCTTCGAAAGATATTGCAAGCATCTCATTAAAGGATAATATCCAGTTTT
CAATACAAGGGAAGGGAGTTAAGCGACTAGCACTGCAGTCCAACATATCAGAAATTGCAAGTACTGCCATTCAAACGGAA
GCTGGTAATTTTTTCAAAGTTGAAGCAGAAACCAGAATATCAACAGAAATGGCTGAACAATTGAGGTATGGAATGGAAGG
CCAATTTGTCGTGATTACAGGTAAGAAGACGTATTTTCAATATTTCATAGATGAATTTTTAGGTAAGGAATAG

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

48.998

99.778

0.489
  comB Streptococcus pneumoniae D39

47.111

100

0.471
  comB Streptococcus pneumoniae R6

47.111

100

0.471
  comB Streptococcus pneumoniae Rx1

47.111

100

0.471
  comB Streptococcus pneumoniae TIGR4

46.667

100

0.467
  comB Streptococcus mitis NCTC 12261

45.778

100

0.458
  comB Streptococcus mitis SK321

45.556

100

0.456