Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NWE22_RS00310 Genome accession   NZ_CP102747
Coordinates   52254..54407 (+) Length   717 a.a.
NCBI ID   WP_277745484.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 47254..59407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS00295 (NWE22_00295) - 47918..48664 (+) 747 WP_277745482.1 hypothetical protein -
  NWE22_RS00300 (NWE22_00300) - 48669..50381 (+) 1713 WP_277745483.1 ABC transporter ATP-binding protein -
  NWE22_RS00305 (NWE22_00305) - 50488..51756 (+) 1269 WP_174846490.1 MerR family transcriptional regulator -
  NWE22_RS00310 (NWE22_00310) comA 52254..54407 (+) 2154 WP_277745484.1 peptide cleavage/export ABC transporter ComA Regulator
  NWE22_RS00315 (NWE22_00315) comB 54419..55771 (+) 1353 WP_277745485.1 bacteriocin secretion accessory protein Regulator
  NWE22_RS00320 (NWE22_00320) - 56160..56339 (+) 180 WP_024392853.1 hypothetical protein -
  NWE22_RS00325 (NWE22_00325) - 56340..56540 (+) 201 WP_277745486.1 hypothetical protein -
  NWE22_RS00330 (NWE22_00330) - 56557..56748 (+) 192 WP_024392851.1 hypothetical protein -
  NWE22_RS00335 (NWE22_00335) - 57109..57978 (-) 870 WP_130555553.1 cysteine ABC transporter substrate-binding protein -
  NWE22_RS00340 (NWE22_00340) - 57991..58737 (-) 747 WP_277745487.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81050.31 Da        Isoelectric Point: 7.1946

>NTDB_id=718670 NWE22_RS00310 WP_277745484.1 52254..54407(+) (comA) [Streptococcus parasuis strain SFJ45]
MKFGKRHYRAQVDTRDCGVAALAMILEYYRSHHSLASLREMAKTTMEGTTAFGLVKVAEELGFETRAIKADMSLFSMREA
VYPFIAHVVKDGTLLHYYVVIGADKKYIYIADPDPSVKLTKLSHEQFEKEWTGVSLFMSPKPEYQPHKEKSHGLLSFIPL
LTKQKGLITNIVLATLLVTFINIVGSYYLQSIIDTYVPNQMKTTLGVISVGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIVVVVSVVLFSQNVYLFFISLLALPIYTI
IIFAFMKPFEKMNQEVMESNAILSSSIIEDINGIETIKSLTSEKQRYQKIDREFVDYLQKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGACLVMDQKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTAQVANTRLNEVYLVESEFAEKKSVTDLSLL
SGDIECNKVHYKYGYGRDVLTDINLKIKRGEKVSFVGVSGSGKTTLAKMMVDFYDPYKGEIRLNNVNINQIDKQTLRQHI
NYLPQQPYVFNGTILENLLLGAKEGTSQEDILWAVEMACIREDIEKMPLNYQTGLTSDGAGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLSLDKTLIFIAHRLTIAERTEHIVVLDKGRIVEQGSHKELLDKQGFYEYLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=718670 NWE22_RS00310 WP_277745484.1 52254..54407(+) (comA) [Streptococcus parasuis strain SFJ45]
ATGAAATTTGGAAAACGTCATTATAGAGCACAAGTCGATACACGAGACTGTGGTGTAGCAGCGCTTGCTATGATTTTGGA
ATATTATCGTTCTCATCATTCTTTAGCAAGTTTGCGAGAAATGGCAAAGACAACTATGGAAGGCACGACAGCATTTGGTT
TAGTAAAGGTTGCTGAAGAGCTAGGGTTTGAGACGCGTGCGATTAAGGCAGATATGTCTTTGTTTTCGATGAGGGAAGCG
GTCTATCCTTTCATTGCCCATGTGGTAAAAGATGGCACGTTACTTCATTATTATGTTGTCATTGGGGCAGATAAGAAATA
TATCTATATTGCAGACCCGGATCCATCAGTGAAATTAACAAAGTTATCCCATGAACAATTTGAAAAGGAGTGGACAGGAG
TTTCGCTATTCATGTCTCCCAAACCGGAATATCAACCTCATAAAGAGAAGAGTCATGGGTTACTTTCTTTCATTCCATTG
TTGACTAAACAAAAGGGATTGATTACAAATATTGTTCTTGCAACGCTCTTGGTTACTTTCATCAACATTGTGGGCTCCTA
TTATTTACAATCCATTATTGACACTTATGTTCCAAATCAGATGAAAACAACATTAGGTGTTATTTCAGTCGGTTTGGTGG
TTGTTTATGCCCTGCAACAATTGTTATCTTATGCCCAAGAGTATTTATTAATCATTCTTGGGCAACGACTCTCTATTGAT
GTGATTTTGTCTTATATTAGACATGTTTTTCATCTACCAATGTCATTTTTTGCTACTCGGCGAACTGGGGAAATTGTTTC
ACGATTTACAGATGCCAATTCTATTATTGATGCTTTAGCTAGTACCATTCTATCAATATTTTTGGATGTATCTATTGTTG
TGGTTGTTTCGGTAGTGCTGTTTAGTCAGAATGTCTATCTTTTCTTTATTTCCTTATTGGCATTGCCAATCTATACTATA
ATCATTTTTGCGTTTATGAAACCATTTGAAAAGATGAATCAAGAAGTGATGGAAAGTAATGCAATTCTTTCTTCGTCTAT
TATTGAAGATATTAATGGTATTGAAACCATAAAATCATTGACAAGTGAGAAACAACGTTATCAGAAAATTGATAGAGAAT
TTGTAGATTATTTACAAAAATCATTTGCATACAACAAGGCCGAAGGGCAGCAAAAAGTGTTAAAGCGCTTGGCCCAACTC
GTATTAAATGTAGCAATTCTTTGGTTAGGAGCCTGTCTTGTTATGGATCAGAAAATGACTTTGGGGCAGCTAATCACCTT
CAATACGTTATTGGTCTATTTCACGAATCCATTGGAAAATATAATCAATTTACAAACAAAACTACAGACAGCTCAAGTTG
CCAATACCCGCTTGAACGAGGTCTATTTGGTTGAATCGGAATTTGCTGAAAAGAAATCCGTGACGGACCTTTCGTTACTT
TCGGGGGATATTGAATGCAACAAAGTGCATTATAAATATGGCTATGGTAGGGATGTTTTGACAGATATTAATTTGAAAAT
TAAACGAGGGGAAAAGGTCTCCTTTGTTGGAGTTTCTGGTTCTGGGAAGACGACGTTGGCTAAAATGATGGTGGATTTTT
ATGACCCTTACAAGGGTGAGATTCGATTAAATAATGTCAACATTAATCAAATCGATAAGCAAACACTTCGTCAGCATATT
AATTATCTTCCACAGCAACCCTATGTTTTTAATGGGACAATTCTCGAAAATCTATTGCTAGGTGCAAAAGAGGGAACAAG
TCAAGAAGATATCTTGTGGGCTGTTGAAATGGCATGTATTAGAGAAGATATTGAAAAAATGCCACTGAATTACCAAACGG
GGTTGACTTCTGATGGAGCTGGAATCTCCGGTGGACAACGGCAGCGAATTGCCTTGGCGCGTGCCCTTCTTACGGATGCC
CCTATTATGATTTTGGATGAGGCAACCAGTAGTCTGGATATTTTGACAGAGAAGCGTATTGTGGACAACCTATTGTCATT
GGACAAAACTCTAATTTTTATTGCACATCGGTTAACCATTGCAGAGCGTACTGAACATATTGTTGTGCTAGATAAGGGAA
GAATTGTAGAACAAGGGAGTCATAAGGAATTGTTAGACAAGCAAGGGTTCTATGAATATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus pneumoniae Rx1

79.498

100

0.795
  comA Streptococcus pneumoniae D39

79.498

100

0.795
  comA Streptococcus pneumoniae R6

79.498

100

0.795
  comA Streptococcus mitis NCTC 12261

79.358

100

0.794
  comA Streptococcus pneumoniae TIGR4

79.219

100

0.792
  comA Streptococcus mitis SK321

79.219

100

0.792
  comA Streptococcus gordonii str. Challis substr. CH1

76.987

100

0.77
  comA/nlmT Streptococcus mutans UA159

63.459

100

0.635