Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   EL277_RS06225 Genome accession   NZ_AP018936
Coordinates   1195162..1196010 (-) Length   282 a.a.
NCBI ID   WP_000705302.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NU83127     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1193637..1194590 1195162..1196010 flank 572


Gene organization within MGE regions


Location: 1193637..1196010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS06215 (SPNU_1186) - 1193637..1194590 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  EL277_RS06225 (SPNU_1187) dprA/cilB/dalA 1195162..1196010 (-) 849 WP_000705302.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31090.78 Da        Isoelectric Point: 5.4047

>NTDB_id=71793 EL277_RS06225 WP_000705302.1 1195162..1196010(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain NU83127]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPASILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=71793 EL277_RS06225 WP_000705302.1 1195162..1196010(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain NU83127]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGCTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae D39

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae R6

99.291

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

99.291

100

0.993
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

62.857

99.291

0.624
  dprA Lactococcus lactis subsp. cremoris KW2

55

99.291

0.546
  dprA Staphylococcus aureus N315

37.102

100

0.372

Multiple sequence alignment