Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL414_RS11355 Genome accession   NZ_CP117013
Coordinates   2232338..2232994 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI114     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2227338..2237994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL414_RS11325 (NL414_011325) dcyD 2228218..2229204 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL414_RS11330 (NL414_011330) tcyL 2229219..2229887 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL414_RS11335 (NL414_011335) tcyN 2229884..2230636 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL414_RS11340 (NL414_011340) sdiA 2230866..2231588 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  NL414_RS11345 (NL414_011345) yecF 2231655..2231879 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL414_RS11350 (NL414_011350) yecU 2231866..2232042 (-) 177 WP_000590347.1 protein YecU -
  NL414_RS26195 - 2232125..2232196 (-) 72 Protein_2128 transcriptional regulator -
  NL414_RS11355 (NL414_011355) letA 2232338..2232994 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL414_RS11360 (NL414_011360) uvrC 2232991..2234823 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NL414_RS11365 (NL414_011365) pgsA 2234880..2235428 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL414_RS11385 (NL414_011385) yecA 2236078..2236743 (+) 666 WP_000847874.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=716092 NL414_RS11355 WP_000611328.1 2232338..2232994(+) (letA) [Escherichia coli strain MLI114]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=716092 NL414_RS11355 WP_000611328.1 2232338..2232994(+) (letA) [Escherichia coli strain MLI114]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCACGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482