Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   OSR41_RS21800 Genome accession   NZ_CP116941
Coordinates   4209085..4210296 (-) Length   403 a.a.
NCBI ID   WP_003177958.1    Uniprot ID   -
Organism   Bacillus licheniformis strain GN02     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4204085..4215296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OSR41_RS21770 (OSR41_21770) rlmH 4204838..4205317 (-) 480 WP_003177946.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  OSR41_RS21775 (OSR41_21775) - 4205398..4205556 (-) 159 WP_003177948.1 CxxH/CxxC protein -
  OSR41_RS21780 (OSR41_21780) - 4205755..4206237 (-) 483 WP_035333986.1 DUF4234 domain-containing protein -
  OSR41_RS21785 (OSR41_21785) - 4206668..4207186 (-) 519 WP_011201784.1 GNAT family N-acetyltransferase -
  OSR41_RS21790 (OSR41_21790) - 4207217..4207687 (-) 471 WP_003177954.1 membrane protein -
  OSR41_RS21795 (OSR41_21795) - 4207943..4208788 (-) 846 WP_075178298.1 SAM hydrolase/SAM-dependent halogenase family protein -
  OSR41_RS21800 (OSR41_21800) htrA 4209085..4210296 (-) 1212 WP_003177958.1 S1C family serine protease Regulator
  OSR41_RS21805 (OSR41_21805) vicX 4210379..4211173 (-) 795 WP_003177960.1 MBL fold metallo-hydrolase Regulator
  OSR41_RS21810 (OSR41_21810) - 4211188..4212036 (-) 849 WP_003177962.1 two-component system regulatory protein YycI -
  OSR41_RS21815 (OSR41_21815) - 4212023..4213387 (-) 1365 WP_003177963.1 YycH family regulatory protein -
  OSR41_RS21820 (OSR41_21820) walK 4213377..4215221 (-) 1845 WP_003177965.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 43091.90 Da        Isoelectric Point: 5.7694

>NTDB_id=715018 OSR41_RS21800 WP_003177958.1 4209085..4210296(-) (htrA) [Bacillus licheniformis strain GN02]
MEFNHDEEKFVREKPVRSWRSFLFSSLVGAVIGALLTVFALPYLSQQGWLPYNLQVIEARGGQGAQQGGTVRNVSVNVNN
EVTQVVSKVSDSVVGVINIQKTGVWDGDSEAGTGSGVIYKKDGNTSHIVTNHHVIEGASQIEISLNDGTRIPAKLIGSDK
LMDLAVLQVNSNKIKAAAEFGDSDKVKTGEPVIAIGNPLGLQFSGSVTQGIISGTERAVPVDSNGDGQPDWNAEVLQTDA
AINPGNSGGGLFNIDGKVIGINSMKIAESAVEGIGLSIPANLAIPVIEDLETYGEVRRPYLGIEMKSLGDIASYHWQETL
KLPKNVTSGVVVMGVQPVSPAGRAGLKELDVIVEFNGDRVYDIVDLRKKLYTKNVGDKVKIKYLRGGKEKTTEVKLTRSQ
LGS

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=715018 OSR41_RS21800 WP_003177958.1 4209085..4210296(-) (htrA) [Bacillus licheniformis strain GN02]
GTGGAGTTTAATCATGATGAGGAAAAATTCGTTCGGGAAAAGCCGGTGAGAAGTTGGAGAAGCTTTTTGTTTTCAAGCCT
GGTCGGCGCCGTCATCGGCGCTCTTTTAACAGTGTTTGCCTTGCCGTATCTCTCGCAGCAGGGATGGCTGCCGTATAATC
TGCAAGTCATCGAAGCGCGCGGCGGCCAAGGAGCACAGCAGGGCGGGACGGTCCGCAATGTATCCGTCAACGTGAATAAT
GAAGTCACGCAAGTGGTCTCTAAGGTTTCTGATTCTGTTGTCGGCGTTATCAACATCCAAAAGACAGGTGTATGGGATGG
TGACAGCGAAGCGGGAACAGGCTCGGGCGTTATTTATAAAAAGGACGGCAACACATCCCACATTGTGACAAACCACCATG
TCATTGAAGGGGCGTCCCAAATAGAAATCAGCCTGAATGACGGAACACGGATTCCGGCAAAACTGATCGGCAGCGATAAG
CTGATGGATCTGGCCGTCCTGCAAGTCAACAGCAACAAAATAAAAGCAGCTGCCGAATTTGGAGATTCTGATAAAGTGAA
GACAGGCGAGCCTGTCATCGCGATTGGAAACCCGCTCGGCCTGCAGTTTTCAGGCTCTGTTACACAAGGAATCATCTCAG
GAACCGAACGCGCTGTGCCGGTCGATTCCAACGGAGACGGACAGCCGGACTGGAACGCCGAAGTACTGCAGACGGATGCT
GCCATTAACCCGGGTAACAGCGGAGGCGGGCTGTTTAATATTGATGGAAAAGTCATCGGCATTAATTCGATGAAAATCGC
TGAATCAGCCGTCGAAGGCATCGGTCTGAGCATTCCGGCCAACCTTGCCATTCCGGTTATCGAAGATTTGGAAACGTACG
GTGAAGTGAGACGGCCGTATCTCGGAATTGAGATGAAATCACTTGGCGATATCGCAAGCTACCACTGGCAGGAAACGCTT
AAACTGCCGAAAAACGTAACATCAGGCGTAGTTGTGATGGGTGTTCAGCCGGTATCTCCTGCAGGCAGAGCCGGTCTGAA
AGAGCTCGATGTCATCGTCGAATTTAACGGTGACCGTGTTTACGATATCGTTGATCTGCGTAAAAAGCTTTACACCAAAA
ACGTCGGCGACAAGGTAAAAATCAAATACCTGCGGGGCGGAAAAGAAAAGACAACAGAAGTAAAGCTGACCCGATCCCAA
TTAGGAAGCTGA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(299-396)

Peptidase family M50 (Peptidase_M50)

(240-398)

Trypsin-like peptidase domain (Trypsin_2)

(114-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

43.799

94.045

0.412
  htrA Streptococcus mutans UA159

45.17

87.345

0.395
  htrA Streptococcus pneumoniae D39

46.847

82.63

0.387
  htrA Streptococcus pneumoniae TIGR4

46.847

82.63

0.387
  htrA Streptococcus pneumoniae R6

46.847

82.63

0.387
  htrA Streptococcus pneumoniae Rx1

46.847

82.63

0.387
  htrA Streptococcus gordonii str. Challis substr. CH1

42.693

86.6

0.37