Detailed information NTG0714934

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: NQZ91_RS03735
• Genome accession: NZ_CP102145
• Coordinates: 783212..783886 (-)
• Length: 224 a.a.
• NCBI ID: WP_105110909.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DNS20
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 778212..788886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ91_RS03710 (NQZ91_03710)	-	778602..779879 (-)	1278	WP_257117886.1	pyrimidine-nucleoside phosphorylase	-
NQZ91_RS03715 (NQZ91_03715)	-	779876..780466 (-)	591	WP_105138219.1	class I SAM-dependent methyltransferase	-
NQZ91_RS03720 (NQZ91_03720)	coaA	780575..781495 (+)	921	WP_170239177.1	type I pantothenate kinase	-
NQZ91_RS03725 (NQZ91_03725)	rpsT	781554..781802 (+)	249	WP_170239180.1	30S ribosomal protein S20	-
NQZ91_RS03730 (NQZ91_03730)	-	781864..783222 (-)	1359	WP_257117887.1	cell wall metabolism sensor histidine kinase WalK	-
NQZ91_RS03735 (NQZ91_03735)	ciaR	783212..783886 (-)	675	WP_105110909.1	response regulator transcription factor	Regulator
NQZ91_RS03740 (NQZ91_03740)	rplT	784327..784686 (-)	360	WP_105110910.1	50S ribosomal protein L20	-
NQZ91_RS03745 (NQZ91_03745)	rpmI	784739..784939 (-)	201	WP_024375714.1	50S ribosomal protein L35	-
NQZ91_RS03750 (NQZ91_03750)	infC	784967..785473 (-)	507	WP_105161128.1	translation initiation factor IF-3	-
NQZ91_RS03755 (NQZ91_03755)	cmk	785669..786346 (-)	678	WP_105161127.1	(d)CMP kinase	-
NQZ91_RS03760 (NQZ91_03760)	-	786355..786885 (-)	531	WP_105138224.1	SAG1386/EF1546 family surface-associated protein	-
NQZ91_RS03765 (NQZ91_03765)	-	786934..787128 (+)	195	WP_105110914.1	ferredoxin	-
NQZ91_RS03770 (NQZ91_03770)	-	787096..787605 (-)	510	WP_105138226.1	EbsA family protein	-
NQZ91_RS03775 (NQZ91_03775)	-	787752..788006 (-)	255	WP_170239173.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25491.13 Da
• Isoelectric Point: 4.2134

>NTDB_id=714934 NQZ91_RS03735 WP_105110909.1 783212..783886(-) (ciaR) [Streptococcus suis strain DNS20]
MIKILLVEDDVSLSNSVFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKEIREKGISTPVLITTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNDNQLEFGNVTVDLSTNMTYVDGSEIELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTVFADRLQTLRSVGYILKNDQ

Nucleotide

• Length: 675 bp

>NTDB_id=714934 NQZ91_RS03735 WP_105110909.1 783212..783886(-) (ciaR) [Streptococcus suis strain DNS20]
ATGATTAAAATATTGCTTGTTGAAGACGATGTAAGCCTATCTAATTCGGTGTTCGACTTTCTAGATGATTTTGCTGATGT
TATGCAGGTTTTTGATGGCGATGAGGGCCTCTATGAGGCAGAATCAGGTGTCTATGATCTGATTCTCTTGGATCTGATGT
TGCCAGAGAAGGATGGATTTCAGGTCTTAAAAGAAATCCGCGAAAAAGGAATTTCTACTCCGGTCCTGATTACGACGGCT
AAAGAAAGCTTGGATGATAAGGGTCACGGTTTTGAATTGGGGGCGGATGATTACCTGACCAAGCCATTTTATTTAGAGGA
GTTGAAGATGCGTATTCAGGCGCTTTTGAAGCGAGCTGGTAAATTCAATGATAATCAGCTAGAATTTGGCAATGTGACTG
TTGATTTGTCTACCAATATGACCTATGTGGACGGCAGTGAAATTGAGTTACTAGGAAAAGAATTTGATTTACTGGTGTAT
TTCTTGCAAAACCAGAACGTTATTCTTCCTAAAACTCAAATTTTTGACCGTATTTGGGGCTTTGACAGCGATACGACCAT
CTCAGTAGTAGAGGTCTATGTTTCAAAAGTCCGAAAGAAATTAAAGGGAACGGTTTTCGCAGACCGCTTGCAGACCTTGA
GAAGTGTAGGGTATATTTTGAAAAATGATCAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	86.607	100	0.866
ciaR	Streptococcus pneumoniae D39	86.607	100	0.866
ciaR	Streptococcus pneumoniae R6	86.607	100	0.866
ciaR	Streptococcus pneumoniae TIGR4	86.607	100	0.866
ciaR	Streptococcus mutans UA159	86.036	99.107	0.853
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.611	100	0.379
micA	Streptococcus pneumoniae Cp1015	35.043	100	0.366
covR	Streptococcus salivarius strain HSISS4	35.193	100	0.366