Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NQZ97_RS00390 Genome accession   NZ_CP102136
Coordinates   68053..68952 (+) Length   299 a.a.
NCBI ID   WP_004195451.1    Uniprot ID   A0AA87K4R4
Organism   Streptococcus suis strain M105052_S26     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 43901..67291 68053..68952 flank 762


Gene organization within MGE regions


Location: 43901..68952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ97_RS00295 (NQZ97_00295) - 43934..44686 (+) 753 WP_257110617.1 ABC transporter permease -
  NQZ97_RS00300 (NQZ97_00300) - 45465..51380 (+) 5916 WP_257110618.1 ZmpA/ZmpB/ZmpC family metallo-endopeptidase -
  NQZ97_RS00305 (NQZ97_00305) - 51918..52265 (-) 348 Protein_40 transposase -
  NQZ97_RS00310 (NQZ97_00310) purD 52576..53838 (+) 1263 WP_170244151.1 phosphoribosylamine--glycine ligase -
  NQZ97_RS00315 (NQZ97_00315) purE 53864..54352 (+) 489 WP_170238144.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  NQZ97_RS00320 (NQZ97_00320) purK 54339..55412 (+) 1074 WP_170238145.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  NQZ97_RS00325 (NQZ97_00325) - 55522..56385 (+) 864 WP_105130724.1 hypothetical protein -
  NQZ97_RS00330 (NQZ97_00330) purB 56665..57957 (+) 1293 WP_256787690.1 adenylosuccinate lyase -
  NQZ97_RS00335 (NQZ97_00335) - 58998..59726 (+) 729 WP_052497005.1 hypothetical protein -
  NQZ97_RS00340 (NQZ97_00340) - 59736..60314 (+) 579 WP_256787689.1 CPBP family intramembrane glutamic endopeptidase -
  NQZ97_RS00345 (NQZ97_00345) - 60329..60757 (+) 429 WP_043025652.1 Msa family membrane protein -
  NQZ97_RS00350 (NQZ97_00350) - 60750..61622 (+) 873 WP_029177681.1 ABC transporter ATP-binding protein -
  NQZ97_RS00355 (NQZ97_00355) - 61628..62401 (+) 774 WP_029179963.1 membrane protein -
  NQZ97_RS00360 (NQZ97_00360) - 62404..64116 (+) 1713 WP_170238150.1 ABC transporter ATP-binding protein -
  NQZ97_RS00365 (NQZ97_00365) - 64130..64417 (+) 288 WP_249338908.1 hypothetical protein -
  NQZ97_RS00370 (NQZ97_00370) - 64529..64702 (+) 174 WP_162840697.1 hypothetical protein -
  NQZ97_RS00375 (NQZ97_00375) - 64828..66096 (+) 1269 WP_170238151.1 MerR family transcriptional regulator -
  NQZ97_RS00380 (NQZ97_00380) ruvB 66290..67291 (+) 1002 WP_105127845.1 Holliday junction branch migration DNA helicase RuvB -
  NQZ97_RS00385 (NQZ97_00385) - 67359..67982 (+) 624 WP_044672706.1 HAD-IA family hydrolase -
  NQZ97_RS00390 (NQZ97_00390) comR 68053..68952 (+) 900 WP_004195451.1 helix-turn-helix domain-containing protein Regulator

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35314.19 Da        Isoelectric Point: 4.3390

>NTDB_id=714604 NQZ97_RS00390 WP_004195451.1 68053..68952(+) (comR) [Streptococcus suis strain M105052_S26]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYENEELMEKRADMMTEIYDDYYDDLPEEEKIAIDAIQSIIDVFETKTAEFGQDILEDYFEQIQRKTQFSAND
LLIIRLYLINLRIEIKQSSDFQHFLELVEKLPSQVELIESGELFILRDVMLTSIGILGEHEEYGKIPPLFDALDRIMVST
QDFQKKPILNLLKWKYELYVNNDSEEARRFYEEAVMFAKLIGDSHLVEKLESSWREEEK

Nucleotide


Download         Length: 900 bp        

>NTDB_id=714604 NQZ97_RS00390 WP_004195451.1 68053..68952(+) (comR) [Streptococcus suis strain M105052_S26]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCAACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCAGATTATGTGTCGCTACCTGAACGATATTCCAAACTGAAG
TTTGATGTCCTCCGTACACCGACTTATGAAAATGAGGAATTGATGGAAAAACGTGCAGATATGATGACAGAAATCTATGA
TGACTATTATGATGACTTGCCTGAAGAAGAGAAAATAGCGATTGATGCCATTCAATCCATTATTGATGTATTTGAAACGA
AGACAGCAGAATTTGGTCAAGATATTCTAGAAGATTATTTTGAACAAATCCAAAGAAAAACCCAATTTTCAGCCAACGAT
TTGTTGATAATTCGACTCTATTTAATCAATTTGAGAATAGAAATTAAACAGAGCAGTGATTTTCAGCACTTTTTAGAGTT
GGTGGAAAAGTTACCCAGCCAAGTAGAATTGATTGAATCTGGAGAATTATTTATTTTAAGAGATGTGATGCTGACGTCGA
TAGGGATTCTTGGCGAACATGAAGAATATGGCAAGATACCTCCACTTTTTGATGCTCTAGATAGAATCATGGTTTCAACT
CAAGATTTTCAAAAGAAACCCATTCTCAATCTGCTTAAGTGGAAATATGAGTTGTATGTGAACAATGATAGCGAGGAGGC
TAGACGGTTTTATGAAGAAGCAGTTATGTTCGCAAAATTAATTGGAGACTCCCATTTAGTAGAAAAATTAGAATCATCAT
GGAGAGAAGAGGAAAAGTGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

68.136

98.662

0.672
  comR Streptococcus suis 05ZYH33

68.136

98.662

0.672
  comR Streptococcus suis D9

61.538

100

0.615
  comR Streptococcus mutans UA159

42.475

100

0.425
  comR Streptococcus pyogenes MGAS8232

38.384

99.331

0.381
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.889

96.321

0.375
  comR Streptococcus pyogenes MGAS315

36.824

98.997

0.365