Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NQZ98_RS03750 Genome accession   NZ_CP102135
Coordinates   716301..717005 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis strain M106471_S40     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 711301..722005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS03730 (NQZ98_03730) - 713109..713768 (-) 660 WP_024384909.1 amino acid ABC transporter permease -
  NQZ98_RS03735 (NQZ98_03735) - 713783..714481 (-) 699 WP_141590556.1 amino acid ABC transporter permease -
  NQZ98_RS03740 (NQZ98_03740) - 714496..715335 (-) 840 WP_044668291.1 transporter substrate-binding domain-containing protein -
  NQZ98_RS03745 (NQZ98_03745) - 715346..716107 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NQZ98_RS03750 (NQZ98_03750) micA 716301..717005 (+) 705 WP_002935840.1 response regulator YycF Regulator
  NQZ98_RS03755 (NQZ98_03755) micB 716998..718347 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NQZ98_RS03760 (NQZ98_03760) vicX 718354..719157 (+) 804 WP_014637679.1 MBL fold metallo-hydrolase Regulator
  NQZ98_RS03765 (NQZ98_03765) vga(F) 719415..720800 (+) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=714575 NQZ98_RS03750 WP_002935840.1 716301..717005(+) (micA) [Streptococcus suis strain M106471_S40]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=714575 NQZ98_RS03750 WP_002935840.1 716301..717005(+) (micA) [Streptococcus suis strain M106471_S40]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTCACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGTAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376