NTDB

Overview

Name	micA	Type	Regulator
Locus tag	NQZ84_RS07325	Genome accession	NZ_CP102094
Coordinates	1486803..1487507 (-)	Length	234 a.a.
NCBI ID	WP_002935840.1	Uniprot ID	A0A0M9FML3
Organism	Streptococcus suis strain 12RC1
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1481803..1492507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ84_RS07310 (NQZ84_07310)	vga(F)	1483008..1484393 (-)	1386	WP_014637680.1	ABC-F type ribosomal protection protein Vga(F)	-
NQZ84_RS07315 (NQZ84_07315)	vicX	1484651..1485454 (-)	804	WP_014637679.1	MBL fold metallo-hydrolase	Regulator
NQZ84_RS07320 (NQZ84_07320)	micB	1485461..1486810 (-)	1350	WP_002935841.1	cell wall metabolism sensor histidine kinase VicK	Regulator
NQZ84_RS07325 (NQZ84_07325)	micA	1486803..1487507 (-)	705	WP_002935840.1	response regulator YycF	Regulator
NQZ84_RS07330 (NQZ84_07330)	-	1487701..1488462 (+)	762	WP_044681329.1	amino acid ABC transporter ATP-binding protein	-
NQZ84_RS07335 (NQZ84_07335)	-	1488473..1489312 (+)	840	WP_044681327.1	transporter substrate-binding domain-containing protein	-
NQZ84_RS07340 (NQZ84_07340)	-	1489327..1490025 (+)	699	WP_013730248.1	amino acid ABC transporter permease	-
NQZ84_RS07345 (NQZ84_07345)	-	1490040..1490699 (+)	660	WP_044677431.1	amino acid ABC transporter permease	-

Sequence

Protein

Download Length: 234 a.a. Molecular weight: 26751.75 Da Isoelectric Point: 4.8957

                                >NTDB_id=714310 NQZ84_RS07325 WP_002935840.1 1486803..1487507(-) (micA) [Streptococcus suis strain 12RC1]

MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA

KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT

HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide

Download Length: 705 bp

                                >NTDB_id=714310 NQZ84_RS07325 WP_002935840.1 1486803..1487507(-) (micA) [Streptococcus suis strain 12RC1]

ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA

AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA

TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT

AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA

ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC

CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTAGAGCTGACC

CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT

TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC

CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
micA	Streptococcus pneumoniae Cp1015	81.545	99.573	0.812
vicR	Streptococcus mutans UA159	80	100	0.803
covR	Lactococcus lactis subsp. lactis strain DGCC12653	44.783	98.291	0.44
covR	Streptococcus salivarius strain HSISS4	43.723	98.718	0.432
scnR	Streptococcus mutans UA159	38.095	98.718	0.376

Detailed information NTG0714310