Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NPS16_RS00355 Genome accession   NZ_CP101986
Coordinates   58261..59175 (+) Length   304 a.a.
NCBI ID   WP_258969024.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53261..64175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS00325 (NPS16_00325) - 53712..53993 (+) 282 WP_002266371.1 hypothetical protein -
  NPS16_RS00330 (NPS16_00330) - 53987..54412 (+) 426 WP_002266372.1 SRPBCC family protein -
  NPS16_RS00335 (NPS16_00335) - 54443..55483 (+) 1041 WP_002266373.1 hypothetical protein -
  NPS16_RS00340 (NPS16_00340) - 55476..55616 (+) 141 WP_002266374.1 hypothetical protein -
  NPS16_RS00345 (NPS16_00345) purB 55871..57169 (+) 1299 WP_258969023.1 adenylosuccinate lyase -
  NPS16_RS00350 (NPS16_00350) - 57189..57875 (+) 687 WP_002264678.1 DNA alkylation repair protein -
  NPS16_RS00355 (NPS16_00355) comR 58261..59175 (+) 915 WP_258969024.1 helix-turn-helix domain-containing protein Regulator
  NPS16_RS00360 (NPS16_00360) - 59706..61550 (-) 1845 WP_258969025.1 carbohydrate-binding domain-containing protein -
  NPS16_RS00365 (NPS16_00365) - 62048..62323 (+) 276 WP_002283786.1 hypothetical protein -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 35257.41 Da        Isoelectric Point: 5.2885

>NTDB_id=713623 NPS16_RS00355 WP_258969024.1 58261..59175(+) (comR) [Streptococcus mutans strain COCC33-14]
MLKDFGKKIKSLRLEKGLTKEAVCRDESQLSIRQLTRIESGQSTPTLNKAVYIAGRLGVTLGYLTDGENVELPSRYKELK
YLLLRTPTYGDQQRLAEKETYFDEIFSQFYDDLPEEEQLIIDGLQSKLDIHFSDNIDFGVGILNDYFDQILRKTNYQVND
LILIDLYFSCLTVSGLDSAIFDSRKYNQLLETLLKQVDCLPLEDLFVLNNVLLNNFGLLLELKKYDFVKQLIAVSNKIMA
RTHDFQKKPIVNLLTWKHHLFVEKDYAKAKKSYDAAILFAQLTENINLRENLEKEWQKDSQNGT

Nucleotide


Download         Length: 915 bp        

>NTDB_id=713623 NPS16_RS00355 WP_258969024.1 58261..59175(+) (comR) [Streptococcus mutans strain COCC33-14]
ATGTTAAAAGATTTTGGGAAGAAAATTAAGAGCCTGAGGTTAGAAAAGGGGCTGACCAAAGAGGCTGTCTGCCGTGATGA
ATCGCAGTTGTCAATACGGCAGCTGACTAGAATTGAATCAGGACAGTCTACGCCAACTCTTAATAAAGCTGTTTATATTG
CAGGACGTTTAGGAGTAACGCTTGGCTATTTAACGGACGGAGAGAATGTTGAGTTACCCAGTCGTTATAAAGAACTAAAG
TATTTATTATTACGAACGCCAACCTATGGCGACCAACAAAGATTAGCTGAAAAAGAAACCTATTTTGACGAGATTTTTAG
TCAGTTTTATGATGATTTGCCTGAAGAAGAACAATTGATTATTGATGGTTTACAATCGAAACTAGATATTCATTTTAGTG
ACAATATCGATTTTGGCGTTGGTATTTTAAATGACTATTTTGATCAGATTTTAAGAAAAACTAATTATCAGGTCAATGAT
TTGATTCTGATTGATCTCTATTTTTCCTGCTTAACTGTTAGTGGTTTGGATTCAGCTATTTTTGATTCAAGAAAATATAA
TCAATTATTGGAGACATTGCTTAAGCAGGTAGACTGCCTTCCATTGGAAGATCTTTTCGTTTTAAATAATGTTTTATTGA
ATAATTTTGGACTCCTCTTAGAATTGAAAAAATATGATTTTGTTAAGCAGCTTATTGCTGTCAGCAATAAAATCATGGCT
AGAACTCATGATTTTCAAAAAAAGCCTATTGTTAATCTTCTGACATGGAAGCATCATTTATTTGTTGAAAAAGATTATGC
GAAAGCTAAAAAGAGCTATGATGCTGCTATCTTATTTGCCCAGTTAACAGAAAACATTAATTTAAGAGAAAATTTGGAGA
AAGAATGGCAAAAAGATTCTCAGAACGGGACATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(9-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

98.684

100

0.987
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.778

94.737

0.5
  comR Streptococcus pyogenes MGAS8232

47.02

99.342

0.467
  comR Streptococcus pyogenes MGAS315

47.157

98.355

0.464
  comR Streptococcus suis P1/7

43.478

98.355

0.428
  comR Streptococcus suis 05ZYH33

43.478

98.355

0.428
  comR Streptococcus suis D9

37

98.684

0.365