Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   PNF29_RS00360 Genome accession   NZ_CP116773
Coordinates   61943..63145 (+) Length   400 a.a.
NCBI ID   WP_272515834.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM125727     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 56943..68145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PNF29_RS00340 (PNF29_00340) walK 57024..58859 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  PNF29_RS00345 (PNF29_00345) walH 58849..60216 (+) 1368 WP_041054960.1 WalRK two-component regulatory system regulator WalH -
  PNF29_RS00350 (PNF29_00350) walI 60203..61045 (+) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  PNF29_RS00355 (PNF29_00355) vicX 61067..61861 (+) 795 WP_144453088.1 MBL fold metallo-hydrolase Regulator
  PNF29_RS00360 (PNF29_00360) htrA 61943..63145 (+) 1203 WP_272515834.1 serine protease HtrC Regulator
  PNF29_RS00365 (PNF29_00365) - 63165..63295 (+) 131 Protein_70 hypothetical protein -
  PNF29_RS00370 (PNF29_00370) - 63323..63475 (+) 153 Protein_71 ATP-binding protein -
  PNF29_RS00375 (PNF29_00375) rocR 63457..64842 (-) 1386 WP_017695782.1 arginine utilization regulatory protein RocR -
  PNF29_RS00380 (PNF29_00380) rocD 65080..66285 (+) 1206 WP_272515836.1 ornithine aminotransferase -
  PNF29_RS00385 (PNF29_00385) rocE 66508..67911 (+) 1404 WP_017695780.1 amino acid permease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42913.80 Da        Isoelectric Point: 5.5235

>NTDB_id=712960 PNF29_RS00360 WP_272515834.1 61943..63145(+) (htrA) [Bacillus subtilis strain SRCM125727]
MVNYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGVLDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVPADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWYETLKLPK
NVTNGVVVMGVDAFSPAAKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDWVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=712960 PNF29_RS00360 WP_272515834.1 61943..63145(+) (htrA) [Bacillus subtilis strain SRCM125727]
ATGGTGAATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
TCTTAGATCAGCAGCAAAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCAGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTACCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCTGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGTATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGCAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACT
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

Peptidase family M50 (Peptidase_M50)

(218-395)

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.434

99

0.43
  htrA Streptococcus mitis NCTC 12261

43.523

96.5

0.42
  htrA Streptococcus gordonii str. Challis substr. CH1

41.397

100

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378