Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J73_RS03620 Genome accession   NZ_AP018780
Coordinates   718571..719791 (+) Length   406 a.a.
NCBI ID   WP_005660021.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-IV-1 isolate 13H36     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 713571..724791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J73_RS03600 (CHBNIV1_06810) corC 714531..715430 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J73_RS03605 (CHBNIV1_06820) ampD 716053..716616 (-) 564 WP_005660014.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J73_RS03610 (CHBNIV1_06830) pilA 716731..717180 (+) 450 WP_005660016.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J73_RS03615 (CHBNIV1_06840) pilB 717177..718574 (+) 1398 WP_005660019.1 GspE/PulE family protein Machinery gene
  K6J73_RS03620 (CHBNIV1_06850) pilC 718571..719791 (+) 1221 WP_005660021.1 type II secretion system F family protein Machinery gene
  K6J73_RS03625 (CHBNIV1_06860) pilD 719788..720480 (+) 693 WP_221253448.1 A24 family peptidase Machinery gene
  K6J73_RS03630 (CHBNIV1_06870) rho 720534..721796 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J73_RS03635 (CHBNIV1_06880) metJ 722043..722360 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J73_RS03640 (CHBNIV1_06890) cueR 722374..722760 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  K6J73_RS03645 (CHBNIV1_06900) - 722837..723043 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J73_RS03650 (CHBNIV1_06910) - 723118..723324 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  K6J73_RS03655 (CHBNIV1_06920) - 723398..723604 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46233.46 Da        Isoelectric Point: 9.7152

>NTDB_id=71289 K6J73_RS03620 WP_005660021.1 718571..719791(+) (pilC) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQDCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEVQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=71289 K6J73_RS03620 WP_005660021.1 718571..719791(+) (pilC) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAGATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGTACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment