Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   K6J73_RS03625 Genome accession   NZ_AP018780
Coordinates   719788..720480 (+) Length   230 a.a.
NCBI ID   WP_221253448.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-IV-1 isolate 13H36     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 714788..725480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J73_RS03605 (CHBNIV1_06820) ampD 716053..716616 (-) 564 WP_005660014.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J73_RS03610 (CHBNIV1_06830) pilA 716731..717180 (+) 450 WP_005660016.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J73_RS03615 (CHBNIV1_06840) pilB 717177..718574 (+) 1398 WP_005660019.1 GspE/PulE family protein Machinery gene
  K6J73_RS03620 (CHBNIV1_06850) pilC 718571..719791 (+) 1221 WP_005660021.1 type II secretion system F family protein Machinery gene
  K6J73_RS03625 (CHBNIV1_06860) pilD 719788..720480 (+) 693 WP_221253448.1 A24 family peptidase Machinery gene
  K6J73_RS03630 (CHBNIV1_06870) rho 720534..721796 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  K6J73_RS03635 (CHBNIV1_06880) metJ 722043..722360 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J73_RS03640 (CHBNIV1_06890) cueR 722374..722760 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  K6J73_RS03645 (CHBNIV1_06900) - 722837..723043 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  K6J73_RS03650 (CHBNIV1_06910) - 723118..723324 (+) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  K6J73_RS03655 (CHBNIV1_06920) - 723398..723604 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26818.86 Da        Isoelectric Point: 9.1329

>NTDB_id=71290 K6J73_RS03625 WP_221253448.1 719788..720480(+) (pilD) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEVFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=71290 K6J73_RS03625 WP_221253448.1 719788..720480(+) (pilD) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACACG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGTCTTTGGACGGGGAGATTATTGGTTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACTTTACCGCACTT
TTTATTATTAGCTTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAGAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

96.087

100

0.961
  pilD Haemophilus influenzae Rd KW20

94.348

100

0.943

Multiple sequence alignment