Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   K6J73_RS02950 Genome accession   NZ_AP018780
Coordinates   592321..593658 (+) Length   445 a.a.
NCBI ID   WP_048951464.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-IV-1 isolate 13H36     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 587321..598658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J73_RS02925 (CHBNIV1_05500) - 587386..589980 (-) 2595 WP_221253385.1 penicillin-binding protein 1A -
  K6J73_RS02930 (CHBNIV1_05510) comA 590079..590876 (+) 798 WP_105872257.1 pilus assembly protein PilM Machinery gene
  K6J73_RS02935 (CHBNIV1_05520) comB 590877..591383 (+) 507 WP_005656467.1 competence protein ComB Machinery gene
  K6J73_RS02940 (CHBNIV1_05530) comC 591380..591901 (+) 522 WP_105872258.1 competence protein ComC Machinery gene
  K6J73_RS02945 (CHBNIV1_05540) comD 591898..592311 (+) 414 WP_048951463.1 pilus assembly protein PilP Machinery gene
  K6J73_RS02950 (CHBNIV1_05550) comE 592321..593658 (+) 1338 WP_048951464.1 type IV pilus secretin PilQ family protein Machinery gene
  K6J73_RS02955 (CHBNIV1_05560) - 593671..594357 (+) 687 WP_221253386.1 ComF family protein -
  K6J73_RS02960 (CHBNIV1_05570) nfuA 594433..595029 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  K6J73_RS02965 (CHBNIV1_05580) nudC 595096..595890 (+) 795 WP_221253387.1 NAD(+) diphosphatase -
  K6J73_RS02970 (CHBNIV1_05590) - 595926..596516 (+) 591 WP_118804715.1 YjaG family protein -
  K6J73_RS02975 (CHBNIV1_05600) - 596656..596928 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49199.45 Da        Isoelectric Point: 7.4787

>NTDB_id=71282 K6J73_RS02950 WP_048951464.1 592321..593658(+) (comE) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVMDERLEGNISLKLDNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=71282 K6J73_RS02950 WP_048951464.1 592321..593658(+) (comE) [Haemophilus influenzae strain CHBN-IV-1 isolate 13H36]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGATGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAGATAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGCTGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAGCA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTA
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAACAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCTGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGCAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.876

100

0.989
  comE Haemophilus influenzae Rd KW20

97.753

100

0.978
  comE Glaesserella parasuis strain SC1401

52.235

95.506

0.499
  pilQ Vibrio campbellii strain DS40M4

43.198

94.157

0.407
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.476

92.584

0.393
  pilQ Vibrio cholerae strain A1552

42.476

92.584

0.393

Multiple sequence alignment