Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J60_RS03845 Genome accession   NZ_AP018778
Coordinates   746064..747281 (+) Length   405 a.a.
NCBI ID   WP_112074625.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-7 isolate 15H01     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 741064..752281
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J60_RS03825 (CHBNIII7_07250) corC 742026..742925 (-) 900 WP_005662987.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J60_RS03830 (CHBNIII7_07260) ampD 743558..744112 (-) 555 WP_112074623.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J60_RS03835 (CHBNIII7_07270) pilA 744227..744676 (+) 450 WP_112074624.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J60_RS03840 (CHBNIII7_07280) pilB 744673..746067 (+) 1395 WP_221267468.1 GspE/PulE family protein Machinery gene
  K6J60_RS03845 (CHBNIII7_07290) pilC 746064..747281 (+) 1218 WP_112074625.1 type II secretion system F family protein Machinery gene
  K6J60_RS03850 (CHBNIII7_07300) pilD 747278..747970 (+) 693 WP_118787909.1 A24 family peptidase Machinery gene
  K6J60_RS03855 (CHBNIII7_07310) rho 748024..749286 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  K6J60_RS03860 (CHBNIII7_07320) metJ 749534..749851 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J60_RS03865 (CHBNIII7_07330) cueR 749865..750251 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K6J60_RS03870 (CHBNIII7_07340) - 750328..750534 (+) 207 WP_048941374.1 heavy-metal-associated domain-containing protein -
  K6J60_RS03875 (CHBNIII7_07350) - 750620..750826 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J60_RS03880 (CHBNIII7_07360) - 750912..751118 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46093.24 Da        Isoelectric Point: 9.7233

>NTDB_id=71218 K6J60_RS03845 WP_112074625.1 746064..747281(+) (pilC) [Haemophilus influenzae strain CHBN-III-7 isolate 15H01]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIQLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=71218 K6J60_RS03845 WP_112074625.1 746064..747281(+) (pilC) [Haemophilus influenzae strain CHBN-III-7 isolate 15H01]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCAGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment