Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J66_RS03570 Genome accession   NZ_AP018771
Coordinates   709989..711209 (+) Length   406 a.a.
NCBI ID   WP_038439228.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-II-8 isolate 10H27     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 704989..716209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J66_RS03550 (CHBNII8_06760) corC 705961..706860 (-) 900 WP_038439233.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J66_RS03555 (CHBNII8_06770) ampD 707483..708034 (-) 552 WP_038439232.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J66_RS03560 (CHBNII8_06780) pilA 708149..708598 (+) 450 WP_038439231.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J66_RS03565 (CHBNII8_06790) pilB 708595..709992 (+) 1398 WP_038439229.1 GspE/PulE family protein Machinery gene
  K6J66_RS03570 (CHBNII8_06800) pilC 709989..711209 (+) 1221 WP_038439228.1 type II secretion system F family protein Machinery gene
  K6J66_RS03575 (CHBNII8_06810) pilD 711206..711898 (+) 693 WP_038439227.1 A24 family peptidase Machinery gene
  K6J66_RS03580 (CHBNII8_06820) rho 711953..713215 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  K6J66_RS03585 (CHBNII8_06830) metJ 713463..713780 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J66_RS03590 (CHBNII8_06840) cueR 713794..714180 (-) 387 WP_038439225.1 Cu(I)-responsive transcriptional regulator -
  K6J66_RS03595 (CHBNII8_06850) - 714257..714463 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J66_RS03600 (CHBNII8_06860) - 714537..714743 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46182.43 Da        Isoelectric Point: 9.6187

>NTDB_id=70972 K6J66_RS03570 WP_038439228.1 709989..711209(+) (pilC) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISCGLTHIKLQQNWQFVAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=70972 K6J66_RS03570 WP_038439228.1 709989..711209(+) (pilC) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCTGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGTGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACACTACTACAATCTGCCATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

96.798

100

0.968
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment