Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   K6J66_RS03575 Genome accession   NZ_AP018771
Coordinates   711206..711898 (+) Length   230 a.a.
NCBI ID   WP_038439227.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-II-8 isolate 10H27     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 706206..716898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J66_RS03555 (CHBNII8_06770) ampD 707483..708034 (-) 552 WP_038439232.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J66_RS03560 (CHBNII8_06780) pilA 708149..708598 (+) 450 WP_038439231.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J66_RS03565 (CHBNII8_06790) pilB 708595..709992 (+) 1398 WP_038439229.1 GspE/PulE family protein Machinery gene
  K6J66_RS03570 (CHBNII8_06800) pilC 709989..711209 (+) 1221 WP_038439228.1 type II secretion system F family protein Machinery gene
  K6J66_RS03575 (CHBNII8_06810) pilD 711206..711898 (+) 693 WP_038439227.1 A24 family peptidase Machinery gene
  K6J66_RS03580 (CHBNII8_06820) rho 711953..713215 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  K6J66_RS03585 (CHBNII8_06830) metJ 713463..713780 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J66_RS03590 (CHBNII8_06840) cueR 713794..714180 (-) 387 WP_038439225.1 Cu(I)-responsive transcriptional regulator -
  K6J66_RS03595 (CHBNII8_06850) - 714257..714463 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J66_RS03600 (CHBNII8_06860) - 714537..714743 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  K6J66_RS03605 (CHBNII8_06870) - 714718..716886 (+) 2169 WP_038439223.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26759.77 Da        Isoelectric Point: 8.8544

>NTDB_id=70973 K6J66_RS03575 WP_038439227.1 711206..711898(+) (pilD) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
MIYFAMFLLGGILGIALWFYLSGFITRLQQEIYATYIELFPQNFLSFQPSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTPCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYTIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=70973 K6J66_RS03575 WP_038439227.1 711206..711898(+) (pilD) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
ATGATTTACTTCGCAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTTTCATTTCAGCCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGGCTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGCTACTTACAATCGGTTTATTTGGCGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGTATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACACAATCTATTGGATTGCAAAATTCTATTACGGC
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTGCCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCGGCTGTCATCATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae Rd KW20

90.87

100

0.909
  pilD Haemophilus influenzae 86-028NP

90.87

100

0.909

Multiple sequence alignment