Detailed information NTG0706080

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: NLS69_RS10590
• Genome accession: NZ_CP100653
• Coordinates: 2230554..2232779 (+)
• Length: 741 a.a.
• NCBI ID: WP_003113988.1
• Uniprot ID: Q9HZM0
• Organism: Pseudomonas aeruginosa strain F13
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2225554..2237779

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLS69_RS10565 (NLS69_10565)	-	2225860..2226459 (-)	600	WP_003105196.1	PilZ domain-containing protein	-
NLS69_RS10570 (NLS69_10570)	-	2226562..2227812 (+)	1251	WP_254575237.1	lipoprotein-releasing ABC transporter permease subunit	-
NLS69_RS10575 (NLS69_10575)	lolD	2227805..2228488 (+)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
NLS69_RS10580 (NLS69_10580)	-	2228558..2229802 (+)	1245	WP_023085389.1	lipoprotein-releasing ABC transporter permease subunit	-
NLS69_RS10585 (NLS69_10585)	-	2229890..2230423 (-)	534	WP_003091165.1	DUF2062 domain-containing protein	-
NLS69_RS10590 (NLS69_10590)	comA	2230554..2232779 (+)	2226	WP_003113988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NLS69_RS10595 (NLS69_10595)	exbB	2232852..2233487 (+)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
NLS69_RS10600 (NLS69_10600)	-	2233484..2233924 (+)	441	WP_003091161.1	biopolymer transporter ExbD	-
NLS69_RS10605 (NLS69_10605)	lpxK	2233924..2234922 (+)	999	WP_025271185.1	tetraacyldisaccharide 4'-kinase	-
NLS69_RS10610 (NLS69_10610)	-	2234960..2235145 (+)	186	WP_003091157.1	Trm112 family protein	-
NLS69_RS10615 (NLS69_10615)	kdsB	2235145..2235909 (+)	765	WP_003130694.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
NLS69_RS10620 (NLS69_10620)	-	2235909..2236373 (+)	465	WP_033983129.1	low molecular weight protein-tyrosine-phosphatase	-
NLS69_RS10625 (NLS69_10625)	murB	2236370..2237389 (+)	1020	WP_025271183.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79979.60 Da
• Isoelectric Point: 10.3506

>NTDB_id=706080 NLS69_RS10590 WP_003113988.1 2230554..2232779(+) (comA) [Pseudomonas aeruginosa strain F13]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLATLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHVLLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPVWLVSGEPARLPSPLFADSCDERSWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=706080 NLS69_RS10590 WP_003113988.1 2230554..2232779(+) (comA) [Pseudomonas aeruginosa strain F13]
ATGCGCCTGGGATTGCCAGCCCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTTGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGGTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCCGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGACGCCTGGCGCCAACGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGCATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCCTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGCGCCTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGCAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCGGGGAGCCTGCTGCTGTGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCGCTTGGCCTGCTGGCGGGCCTGGCCGAGGCCTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCATTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGAGAGCATGTCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGTTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGAGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCACAGGCCGGCG
ACAGCAACGACCGCTCCTGTGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCCCGGGTCGACTGGTTGCTGGCGCCGCATCATGGCAGCCGCAGTTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAGCGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: Q9HZM0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	58.807	97.301	0.572
comA	Ralstonia pseudosolanacearum GMI1000	35.611	100	0.366