Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NLY77_RS05240 Genome accession   NZ_CP100431
Coordinates   1029002..1029844 (-) Length   280 a.a.
NCBI ID   WP_002936492.1    Uniprot ID   -
Organism   Streptococcus suis strain 1521251     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1012222..1068650 1029002..1029844 within 0


Gene organization within MGE regions


Location: 1012222..1068650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS05160 (NLY77_05160) - 1014748..1017099 (-) 2352 WP_172008962.1 VirB4-like conjugal transfer ATPase, CD1110 family -
  NLY77_RS05165 (NLY77_05165) - 1017056..1017409 (-) 354 WP_014636950.1 PrgI family protein -
  NLY77_RS05170 (NLY77_05170) - 1017471..1018325 (-) 855 WP_172008960.1 conjugal transfer protein TrbL -
  NLY77_RS05175 (NLY77_05175) - 1018344..1018586 (-) 243 WP_001072182.1 hypothetical protein -
  NLY77_RS05180 (NLY77_05180) - 1018604..1020421 (-) 1818 WP_172008958.1 VirD4-like conjugal transfer protein, CD1115 family -
  NLY77_RS05185 (NLY77_05185) - 1020421..1020909 (-) 489 WP_002935118.1 hypothetical protein -
  NLY77_RS05190 (NLY77_05190) - 1020987..1021571 (-) 585 WP_172008956.1 CPBP family intramembrane glutamic endopeptidase -
  NLY77_RS05195 (NLY77_05195) - 1021574..1021807 (-) 234 WP_014636955.1 hypothetical protein -
  NLY77_RS05200 (NLY77_05200) - 1021816..1022199 (-) 384 WP_014636956.1 hypothetical protein -
  NLY77_RS05205 (NLY77_05205) - 1022210..1022638 (-) 429 WP_014636957.1 hypothetical protein -
  NLY77_RS05210 (NLY77_05210) dcm 1022622..1023977 (-) 1356 WP_014636958.1 DNA (cytosine-5-)-methyltransferase -
  NLY77_RS05215 (NLY77_05215) - 1024126..1024944 (-) 819 WP_014636959.1 replication initiator protein A -
  NLY77_RS05220 (NLY77_05220) - 1024941..1025114 (-) 174 WP_014636960.1 hypothetical protein -
  NLY77_RS05225 (NLY77_05225) rplL 1025314..1025679 (-) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  NLY77_RS05230 (NLY77_05230) rplJ 1025745..1026239 (-) 495 WP_002936486.1 50S ribosomal protein L10 -
  NLY77_RS05235 (NLY77_05235) topA 1026816..1028909 (-) 2094 WP_024394484.1 type I DNA topoisomerase -
  NLY77_RS05240 (NLY77_05240) dprA 1029002..1029844 (-) 843 WP_002936492.1 DNA-processing protein DprA Machinery gene
  NLY77_RS05245 (NLY77_05245) - 1029903..1030361 (-) 459 Protein_1005 sugar O-acetyltransferase -
  NLY77_RS05250 (NLY77_05250) - 1030506..1030817 (+) 312 WP_014637902.1 rhodanese-like domain-containing protein -
  NLY77_RS05255 (NLY77_05255) - 1030914..1031465 (+) 552 WP_024394485.1 DUF1836 domain-containing protein -
  NLY77_RS05260 (NLY77_05260) - 1031455..1032105 (+) 651 WP_002936498.1 hemolysin III family protein -
  NLY77_RS05265 (NLY77_05265) - 1032138..1033148 (-) 1011 WP_029174502.1 YdcF family protein -
  NLY77_RS05270 (NLY77_05270) - 1033151..1033924 (-) 774 WP_024387771.1 ribonuclease HII -
  NLY77_RS05275 (NLY77_05275) ylqF 1033911..1034762 (-) 852 WP_024394486.1 ribosome biogenesis GTPase YlqF -
  NLY77_RS05280 (NLY77_05280) - 1034854..1036374 (-) 1521 WP_024394487.1 tyrosine-type recombinase/integrase -
  NLY77_RS05285 (NLY77_05285) - 1036464..1036703 (-) 240 WP_004195677.1 hypothetical protein -
  NLY77_RS05290 (NLY77_05290) - 1036989..1037216 (-) 228 WP_023370317.1 helix-turn-helix domain-containing protein -
  NLY77_RS05295 (NLY77_05295) - 1037479..1040406 (-) 2928 WP_024394488.1 glycoside hydrolase family 98 domain-containing protein -
  NLY77_RS05300 (NLY77_05300) - 1040529..1041422 (-) 894 WP_024394489.1 ROK family protein -
  NLY77_RS05305 (NLY77_05305) - 1041432..1043294 (-) 1863 WP_024394490.1 alpha-N-acetylgalactosaminidase -
  NLY77_RS05310 (NLY77_05310) - 1043297..1044619 (-) 1323 WP_172008932.1 alpha-L-fucosidase -
  NLY77_RS05315 (NLY77_05315) - 1044616..1045455 (-) 840 WP_024394492.1 carbohydrate ABC transporter permease -
  NLY77_RS05320 (NLY77_05320) - 1045465..1046385 (-) 921 WP_024394493.1 carbohydrate ABC transporter permease -
  NLY77_RS05325 (NLY77_05325) - 1046444..1047751 (-) 1308 WP_024394494.1 ABC transporter substrate-binding protein -
  NLY77_RS05330 (NLY77_05330) - 1047771..1048418 (-) 648 WP_170244825.1 L-fuculose-phosphate aldolase -
  NLY77_RS05335 (NLY77_05335) - 1048438..1050225 (-) 1788 WP_024394496.1 L-fucose isomerase -
  NLY77_RS05340 (NLY77_05340) - 1050227..1051624 (-) 1398 WP_029750033.1 rhamnulokinase family protein -
  NLY77_RS05345 (NLY77_05345) - 1051787..1052342 (+) 556 Protein_1025 DeoR/GlpR family DNA-binding transcription regulator -
  NLY77_RS05350 (NLY77_05350) mobC 1052349..1052549 (+) 201 WP_230334537.1 plasmid mobilization relaxosome protein MobC -
  NLY77_RS05355 (NLY77_05355) - 1052551..1053846 (+) 1296 WP_024394500.1 relaxase/mobilization nuclease domain-containing protein -
  NLY77_RS05360 (NLY77_05360) - 1053849..1054346 (-) 498 WP_024394501.1 hypothetical protein -
  NLY77_RS05365 (NLY77_05365) - 1054510..1055202 (+) 693 WP_172008938.1 XRE family transcriptional regulator -
  NLY77_RS11560 - 1055205..1055339 (+) 135 WP_087013866.1 hypothetical protein -
  NLY77_RS05370 (NLY77_05370) - 1055345..1056759 (+) 1415 Protein_1031 Y-family DNA polymerase -
  NLY77_RS05375 (NLY77_05375) - 1056756..1057124 (+) 369 WP_024394503.1 hypothetical protein -
  NLY77_RS05380 (NLY77_05380) - 1057111..1057425 (+) 315 WP_024394504.1 DUF5960 family protein -
  NLY77_RS05385 (NLY77_05385) - 1057463..1058233 (-) 771 WP_024394505.1 MurR/RpiR family transcriptional regulator -
  NLY77_RS05390 (NLY77_05390) - 1058246..1058803 (-) 558 WP_024394506.1 DJ-1 family glyoxalase III -
  NLY77_RS05395 (NLY77_05395) - 1058796..1059368 (-) 573 WP_024394507.1 DJ-1 family glyoxalase III -
  NLY77_RS05400 (NLY77_05400) ascB 1059446..1060860 (-) 1415 Protein_1037 6-phospho-beta-glucosidase -
  NLY77_RS05405 (NLY77_05405) - 1060881..1062701 (-) 1821 WP_029174858.1 beta-glucoside-specific PTS transporter subunit IIABC -
  NLY77_RS05410 (NLY77_05410) - 1063505..1064041 (-) 537 WP_226315496.1 CpXC domain-containing protein -
  NLY77_RS05415 (NLY77_05415) - 1064338..1065342 (+) 1005 WP_002935211.1 IS5 family transposase -
  NLY77_RS05420 (NLY77_05420) - 1065433..1065945 (-) 513 WP_172008980.1 single-stranded DNA-binding protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31261.11 Da        Isoelectric Point: 8.4451

>NTDB_id=705258 NLY77_RS05240 WP_002936492.1 1029002..1029844(-) (dprA) [Streptococcus suis strain 1521251]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAIVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=705258 NLY77_RS05240 WP_002936492.1 1029002..1029844(-) (dprA) [Streptococcus suis strain 1521251]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTATAGTGTCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCGCCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATTGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAAGATTTGCAGACCTATATCGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGAAATCGCATCATTGCTGGGTTGG
TAGAAGGATTGGTAGTCTGTGAGGCTAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.286

100

0.693
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.571

100

0.636
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis SK321

63.571

100

0.636
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.357

100

0.604
  dprA Legionella pneumophila strain ERS1305867

41.7

88.214

0.368
  dprA Bacillus subtilis subsp. subtilis str. 168

50.746

71.786

0.364