Detailed information NTG0705230

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: NLY76_RS10510
• Genome accession: NZ_CP100430
• Coordinates: 2167293..2168489 (+)
• Length: 398 a.a.
• NCBI ID: WP_044687195.1
• Uniprot ID: -
• Organism: Streptococcus suis strain LSS42
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2162293..2173489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY76_RS10465 (NLY76_10465)	-	2162990..2163631 (+)	642	WP_044687191.1	replication protein	-
NLY76_RS10470 (NLY76_10470)	-	2163637..2163921 (+)	285	WP_015647601.1	hypothetical protein	-
NLY76_RS10475 (NLY76_10475)	-	2163914..2164249 (+)	336	WP_044687192.1	DUF771 domain-containing protein	-
NLY76_RS10480 (NLY76_10480)	-	2164306..2165427 (+)	1122	WP_044687193.1	site-specific integrase	-
NLY76_RS10500 (NLY76_10500)	-	2165932..2166615 (-)	684	WP_044687194.1	YoaK family protein	-
NLY76_RS10505 (NLY76_10505)	rlmH	2166640..2167119 (-)	480	WP_015647604.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
NLY76_RS10510 (NLY76_10510)	htrA	2167293..2168489 (+)	1197	WP_044687195.1	S1C family serine protease	Regulator
NLY76_RS10515 (NLY76_10515)	spo0J	2168550..2169314 (+)	765	WP_012775418.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41864.86 Da
• Isoelectric Point: 4.5940

>NTDB_id=705230 NLY76_RS10510 WP_044687195.1 2167293..2168489(+) (htrA) [Streptococcus suis strain LSS42]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSTITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSIGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSIYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=705230 NLY76_RS10510 WP_044687195.1 2167293..2168489(+) (htrA) [Streptococcus suis strain LSS42]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTACTATCACTAGTGTCAGCAATGTTCAATACA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTATTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTCATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCATCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACACAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGATCTCCAAAGTGCTCTCTACAAACATCAGATTGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.446	99.749	0.593
htrA	Streptococcus gordonii str. Challis substr. CH1	59.494	99.246	0.59
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565