Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NLY76_RS02985 Genome accession   NZ_CP100430
Coordinates   611967..612671 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain LSS42     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 606967..617671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS02965 (NLY76_02965) - 608775..609434 (-) 660 WP_024389912.1 amino acid ABC transporter permease -
  NLY76_RS02970 (NLY76_02970) - 609449..610147 (-) 699 WP_024389911.1 amino acid ABC transporter permease -
  NLY76_RS02975 (NLY76_02975) - 610162..611001 (-) 840 WP_024389910.1 transporter substrate-binding domain-containing protein -
  NLY76_RS02980 (NLY76_02980) - 611012..611773 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NLY76_RS02985 (NLY76_02985) micA 611967..612671 (+) 705 WP_004298854.1 response regulator YycF Regulator
  NLY76_RS02990 (NLY76_02990) micB 612664..614013 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NLY76_RS02995 (NLY76_02995) vicX 614020..614823 (+) 804 WP_024389909.1 MBL fold metallo-hydrolase Regulator
  NLY76_RS03000 (NLY76_03000) vga(F) 615078..616463 (+) 1386 WP_044770119.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=705205 NLY76_RS02985 WP_004298854.1 611967..612671(+) (micA) [Streptococcus suis strain LSS42]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=705205 NLY76_RS02985 WP_004298854.1 611967..612671(+) (micA) [Streptococcus suis strain LSS42]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGCGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCCGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAAACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
ATGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTAGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376