Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NLY35_RS07395 Genome accession   NZ_CP100418
Coordinates   1494131..1494835 (-) Length   234 a.a.
NCBI ID   WP_204101676.1    Uniprot ID   -
Organism   Streptococcus suis strain STC104     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1489131..1499835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY35_RS07380 (NLY35_07380) vga(F) 1490336..1491721 (-) 1386 WP_254369355.1 ABC-F type ribosomal protection protein Vga(F) -
  NLY35_RS07385 (NLY35_07385) vicX 1491979..1492782 (-) 804 WP_099807080.1 MBL fold metallo-hydrolase Regulator
  NLY35_RS07390 (NLY35_07390) micB 1492789..1494138 (-) 1350 WP_044670912.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NLY35_RS07395 (NLY35_07395) micA 1494131..1494835 (-) 705 WP_204101676.1 response regulator YycF Regulator
  NLY35_RS07400 (NLY35_07400) - 1495029..1495790 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NLY35_RS07405 (NLY35_07405) - 1495801..1496640 (+) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  NLY35_RS07410 (NLY35_07410) - 1496655..1497353 (+) 699 WP_002935835.1 amino acid ABC transporter permease -
  NLY35_RS07415 (NLY35_07415) - 1497368..1498027 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26780.83 Da        Isoelectric Point: 5.1062

>NTDB_id=704981 NLY35_RS07395 WP_204101676.1 1494131..1494835(-) (micA) [Streptococcus suis strain STC104]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPKLVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=704981 NLY35_RS07395 WP_204101676.1 1494131..1494835(-) (micA) [Streptococcus suis strain STC104]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTACCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAAAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376