Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   NEE09_RS01250 Genome accession   NZ_CP099641
Coordinates   242023..242976 (+) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 237023..247976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS01205 - 237086..237451 (+) 366 WP_000286415.1 DUF1033 family protein -
  NEE09_RS01210 comGA/cglA/cilD 237527..238468 (+) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  NEE09_RS01215 comGB/cglB 238416..239432 (+) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  NEE09_RS01220 comGC/cglC 239434..239757 (+) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  NEE09_RS01225 comGD/cglD 239720..240154 (+) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  NEE09_RS01230 comGE/cglE 240117..240419 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  NEE09_RS01235 comGF/cglF 240382..240843 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  NEE09_RS01240 comGG/cglG 240821..241267 (+) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  NEE09_RS01245 - 241370..241962 (+) 593 Protein_226 class I SAM-dependent methyltransferase -
  NEE09_RS01250 comYH 242023..242976 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  NEE09_RS01255 - 243027..244217 (+) 1191 WP_000167765.1 acetate kinase -
  NEE09_RS01260 - 244218..244349 (+) 132 WP_000768904.1 hypothetical protein -
  NEE09_RS01265 rnpA 244366..244737 (+) 372 WP_000739246.1 ribonuclease P protein component -
  NEE09_RS01270 - 244712..245536 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  NEE09_RS01275 jag 245555..246541 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  NEE09_RS01280 - 246592..247215 (+) 624 WP_000932658.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=701175 NEE09_RS01250 WP_000345126.1 242023..242976(+) (comYH) [Streptococcus pneumoniae strain ATCC 700671]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=701175 NEE09_RS01250 WP_000345126.1 242023..242976(+) (comYH) [Streptococcus pneumoniae strain ATCC 700671]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536