Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   NEE09_RS01230 Genome accession   NZ_CP099641
Coordinates   240117..240419 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 235117..245419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS01200 - 235877..236935 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  NEE09_RS01205 - 237086..237451 (+) 366 WP_000286415.1 DUF1033 family protein -
  NEE09_RS01210 comGA/cglA/cilD 237527..238468 (+) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  NEE09_RS01215 comGB/cglB 238416..239432 (+) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  NEE09_RS01220 comGC/cglC 239434..239757 (+) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  NEE09_RS01225 comGD/cglD 239720..240154 (+) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  NEE09_RS01230 comGE/cglE 240117..240419 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  NEE09_RS01235 comGF/cglF 240382..240843 (+) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  NEE09_RS01240 comGG/cglG 240821..241267 (+) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  NEE09_RS01245 - 241370..241962 (+) 593 Protein_226 class I SAM-dependent methyltransferase -
  NEE09_RS01250 comYH 242023..242976 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  NEE09_RS01255 - 243027..244217 (+) 1191 WP_000167765.1 acetate kinase -
  NEE09_RS01260 - 244218..244349 (+) 132 WP_000768904.1 hypothetical protein -
  NEE09_RS01265 rnpA 244366..244737 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=701172 NEE09_RS01230 WP_000413382.1 240117..240419(+) (comGE/cglE) [Streptococcus pneumoniae strain ATCC 700671]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=701172 NEE09_RS01230 WP_000413382.1 240117..240419(+) (comGE/cglE) [Streptococcus pneumoniae strain ATCC 700671]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4