Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SA27298_RS03210 Genome accession   NZ_AP018548
Coordinates   658009..658710 (+) Length   233 a.a.
NCBI ID   WP_003025150.1    Uniprot ID   A0A2I1UXK8
Organism   Streptococcus anginosus strain CCUG 27928     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 653009..663710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS03190 (SA27298_0654) ccpA 653850..654854 (+) 1005 WP_003032767.1 catabolite control protein A Regulator
  SA27298_RS03195 (SA27298_0655) - 655034..656032 (+) 999 WP_022524413.1 glycosyltransferase -
  SA27298_RS03200 (SA27298_0656) - 656034..657347 (+) 1314 WP_003032712.1 glycosyltransferase family 4 protein -
  SA27298_RS03205 - 657374..657715 (+) 342 WP_003032667.1 hypothetical protein -
  SA27298_RS03210 (SA27298_0658) micA 658009..658710 (+) 702 WP_003025150.1 response regulator YycF Regulator
  SA27298_RS03215 (SA27298_0659) micB 658703..660055 (+) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SA27298_RS03220 (SA27298_0660) vicX 660057..660860 (+) 804 WP_003032665.1 MBL fold metallo-hydrolase Regulator
  SA27298_RS03225 - 660869..661226 (+) 358 Protein_599 DUF454 family protein -
  SA27298_RS03230 (SA27298_0664) rnc 661619..662317 (+) 699 WP_003032757.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26887.86 Da        Isoelectric Point: 4.6824

>NTDB_id=69974 SA27298_RS03210 WP_003025150.1 658009..658710(+) (micA) [Streptococcus anginosus strain CCUG 27928]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=69974 SA27298_RS03210 WP_003025150.1 658009..658710(+) (micA) [Streptococcus anginosus strain CCUG 27928]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACTGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTAA
TGTTGCCTGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAGTTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTGCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment