Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SR187_RS01985 Genome accession   NZ_AP018400
Coordinates   381570..383573 (+) Length   667 a.a.
NCBI ID   WP_024532776.1    Uniprot ID   A0A2Z5TNJ9
Organism   Streptococcus ruminantium strain GUT-187     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 376570..388573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS01970 (SR187_2000) fmt 378557..379495 (+) 939 WP_120171347.1 methionyl-tRNA formyltransferase -
  SR187_RS01975 (SR187_2005) rsmB 379482..380795 (+) 1314 WP_120171348.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SR187_RS01980 (SR187_2010) - 380833..381570 (+) 738 WP_120171349.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SR187_RS01985 (SR187_2015) stkP 381570..383573 (+) 2004 WP_024532776.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SR187_RS01990 (SR187_2025) liaF 383776..384471 (+) 696 WP_120172453.1 cell wall-active antibiotics response protein LiaF -
  SR187_RS01995 (SR187_2030) - 384468..385484 (+) 1017 WP_120171350.1 sensor histidine kinase -
  SR187_RS02000 (SR187_2035) - 385456..386097 (+) 642 WP_120171351.1 response regulator transcription factor -
  SR187_RS02005 (SR187_2040) - 386146..387546 (+) 1401 WP_120171352.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SR187_RS02010 (SR187_2045) - 387548..387919 (+) 372 WP_024532771.1 S1 RNA-binding domain-containing protein -
  SR187_RS02015 - 387995..388315 (+) 321 WP_120171353.1 transposase -

Sequence

Protein


Download         Length: 667 a.a.        Molecular weight: 71672.63 Da        Isoelectric Point: 8.7178

>NTDB_id=69437 SR187_RS01985 WP_024532776.1 381570..383573(+) (stkP) [Streptococcus ruminantium strain GUT-187]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVNGLDLKRYIKENAPLSNDVAVRIVGQILLAMRIAHTRGIVHRDLKPQNVLLTSNGVAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVREENANVP
QALENVVLKATAKKLNERYKSVAEMYADLASALSVERRNEPRVELEGNKVDTKTLPKLSQANVDTKSPMANDSVQNVATD
KSVGKKEGIKKPTKSASKPRPGMRTRYKVLIGAILLTALAAGLMFFNTPKTVIVPDVAGQTVEKATEMIEVAGLEVGNVI
KETTKEVGEGLVIRTSPAAKTTKRQGSKVDIVVAIAALVTIPDVSNKSADLARQELEALGFQVSVKEEYSDKVAQGLVIK
TSPEANSSAEQGGKVVLSVSKGVAPQLVPDVVGKTQENATQILQTAGFSIGTITKEHHPSIEAGHVISTDPVANTELTKG
SPVNIVVSKGKELIMPDLVSGNYTYSQARRQLQALGVNIENIERQEDRSYYSTTSDIVIGQYPAAGAVIDGTVTLYVSVA
ASGTNSNSSTGTPSSTSTSTSGTSNGQ

Nucleotide


Download         Length: 2004 bp        

>NTDB_id=69437 SR187_RS01985 WP_024532776.1 381570..383573(+) (stkP) [Streptococcus ruminantium strain GUT-187]
ATGATTCAAATCGGTAAGATCTTTGCTGGGCGCTATCGGATTGTCCGGCAAATTGGTCGAGGCGGTATGGCGGATGTTTA
TCTGGCTAGAGATTTGATTTTGGATGGTGAAGAAGTGGCGGTTAAGGTACTTCGCACTAACTATCAGACGGATCAAATTG
CTATCCAGCGCTTCCAGCGTGAGGCGCGTGCCATGGCGGAGCTTGACCATCCCAATATTGTTCGTATTTCAGATATTGGT
GAAGAAGATGGTCAGCAATACCTTGCAATGGAGTACGTCAACGGTCTCGATTTAAAACGCTATATCAAGGAAAATGCACC
ACTATCAAATGATGTGGCAGTACGAATCGTAGGACAAATTCTTCTTGCTATGCGGATAGCTCATACACGGGGAATTGTTC
ACAGGGATTTGAAACCTCAAAATGTTCTTTTGACATCAAACGGTGTGGCTAAGGTAACGGACTTTGGTATCGCAGTAGCT
TTTGCAGAAACAAGCCTGACACAGACAAATTCTATGTTAGGATCTGTTCACTACCTTTCGCCAGAACAGGCACGTGGTTC
AAAAGCGACCATTCAAAGCGATATTTACGCTATGGGGATTATTCTCTTTGAAATGTTGACTGGTCGAATTCCTTACGATG
GAGATAGTGCTGTTACGATTGCATTGCAACATTTTCAAAAGCCATTACCATCTGTTAGAGAAGAAAATGCGAATGTGCCA
CAAGCATTAGAAAATGTAGTTCTGAAGGCAACTGCTAAAAAGTTGAATGAACGCTATAAATCTGTTGCGGAAATGTATGC
AGACTTAGCTTCAGCCTTGTCTGTGGAACGTCGCAATGAACCGCGGGTTGAGTTGGAGGGCAATAAGGTTGACACAAAGA
CCTTGCCTAAACTTTCTCAGGCAAATGTAGATACTAAGTCTCCTATGGCGAATGATTCTGTTCAAAATGTAGCGACAGAT
AAATCTGTTGGAAAGAAAGAGGGGATTAAAAAGCCAACCAAGTCTGCTTCTAAGCCTAGACCAGGTATGCGCACACGTTA
TAAGGTTCTAATAGGAGCTATTCTTTTGACTGCATTGGCAGCAGGGTTGATGTTTTTCAATACACCTAAAACAGTTATAG
TCCCAGATGTAGCAGGCCAAACGGTTGAAAAAGCCACTGAGATGATTGAAGTGGCAGGATTAGAAGTCGGAAATGTCATC
AAGGAAACGACCAAAGAAGTGGGTGAAGGTTTAGTTATACGGACATCACCAGCAGCAAAAACCACCAAACGTCAAGGGAG
CAAAGTGGATATTGTGGTAGCGATAGCTGCCTTGGTCACTATTCCGGATGTTAGTAATAAATCAGCGGACCTTGCTCGTC
AAGAATTGGAAGCTTTAGGTTTCCAAGTGAGTGTCAAAGAGGAGTATAGTGATAAGGTTGCTCAAGGATTAGTAATAAAG
ACAAGTCCTGAAGCGAATAGTTCTGCTGAACAAGGAGGCAAGGTTGTTCTTTCTGTTTCCAAAGGTGTAGCACCCCAACT
AGTGCCTGATGTCGTTGGAAAAACGCAAGAAAATGCCACCCAGATTCTTCAGACAGCAGGTTTTTCTATTGGAACGATTA
CCAAGGAGCATCATCCTTCAATTGAAGCGGGACATGTCATCAGTACAGATCCTGTTGCGAATACGGAATTAACCAAAGGT
TCACCGGTCAATATCGTAGTTTCTAAAGGAAAAGAGCTAATCATGCCTGACTTGGTCTCTGGGAATTACACCTATTCACA
AGCTCGTAGACAATTACAGGCTCTGGGTGTTAACATAGAAAATATTGAAAGGCAAGAAGATAGAAGCTATTACTCAACCA
CCAGTGATATTGTAATTGGACAATATCCGGCTGCTGGAGCAGTTATTGATGGAACGGTTACTCTGTATGTTTCTGTTGCT
GCGAGTGGAACAAACAGCAACTCCTCTACGGGGACACCATCTAGTACCAGTACTTCAACTAGTGGAACGAGTAATGGACA
GTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(372-433)

PASTA domain (PASTA)

(508-569)

PASTA domain (PASTA)

(574-638)

PASTA domain (PASTA)

(439-501)

Protein kinase domain (Pkinase)

(12-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TNJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

52.623

97.151

0.511
  stkP Streptococcus pneumoniae D39

52.469

97.151

0.51
  stkP Streptococcus pneumoniae R6

52.469

97.151

0.51
  stkP Streptococcus pneumoniae Rx1

52.315

97.151

0.508
  stkP/pknB Streptococcus salivarius strain HSISS4

53.298

84.108

0.448
  pknB Streptococcus mutans UA159

55.576

80.66

0.448

Multiple sequence alignment