Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   M9H69_RS05100 Genome accession   NZ_CP097843
Coordinates   981566..982273 (+) Length   235 a.a.
NCBI ID   WP_250316115.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 976566..987273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS05075 (M9H69_05075) - 976864..977535 (+) 672 WP_250316110.1 GTP pyrophosphokinase family protein -
  M9H69_RS05080 (M9H69_05080) - 977519..978337 (+) 819 WP_250316111.1 NAD kinase -
  M9H69_RS05085 (M9H69_05085) - 978334..979230 (+) 897 WP_250316112.1 RluA family pseudouridine synthase -
  M9H69_RS05090 (M9H69_05090) pta 979274..980248 (+) 975 WP_250316113.1 phosphate acetyltransferase -
  M9H69_RS05095 (M9H69_05095) mutY 980331..981506 (+) 1176 WP_250316114.1 A/G-specific adenine glycosylase -
  M9H69_RS05100 (M9H69_05100) micA 981566..982273 (+) 708 WP_250316115.1 response regulator YycF Regulator
  M9H69_RS05105 (M9H69_05105) micB 982266..983615 (+) 1350 WP_000568719.1 cell wall metabolism sensor histidine kinase VicK Regulator
  M9H69_RS05110 (M9H69_05110) vicX 983617..984426 (+) 810 WP_001290612.1 MBL fold metallo-hydrolase Regulator
  M9H69_RS05115 (M9H69_05115) - 984459..984806 (-) 348 WP_250316116.1 thioredoxin -
  M9H69_RS05120 (M9H69_05120) - 984917..986635 (-) 1719 WP_250316117.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26974.84 Da        Isoelectric Point: 4.6177

>NTDB_id=692925 M9H69_RS05100 WP_250316115.1 981566..982273(+) (micA) [Streptococcus oralis strain HP01]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQESDEKKAQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=692925 M9H69_RS05100 WP_250316115.1 981566..982273(+) (micA) [Streptococcus oralis strain HP01]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCAGAGCAACCTGACATTATTATCCTCGACTTGA
TGTTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGCAAGACCAGTAGTGTTCCTATCATCATGCTCTCAGCC
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAGGCTCGTGTTAAGGCCCTTCTTCGTCGTACCGATCTAGTTTCAGTAGATAACCAAGAGTCTGATGAGAAGAAGG
CGCAACCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCAAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAGCTCTTATATCACTTGGCTTCCCATATTGGACAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTTTGGGGTTATGATTATTTTGGTGATGTTCGGACAGTGGACGTGACTATTAGACGTTTGCGTGAAAAAATTGAAGATA
CTCCAAGCCGTCCAGAGTATATCCTCACCCGTCGTGGTGTTGGCTACTATATGAAAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.88

99.574

0.915
  vicR Streptococcus mutans UA159

77.872

100

0.779
  covR Streptococcus salivarius strain HSISS4

44.156

98.298

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.607

99.574

0.374