Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   STO1_RS04350 Genome accession   NZ_AP018338
Coordinates   851707..852555 (+) Length   282 a.a.
NCBI ID   WP_096422103.1    Uniprot ID   A0A224A6N0
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 846707..857555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS04335 (STO1_008390) - 848225..848953 (+) 729 WP_096422099.1 metallophosphoesterase family protein -
  STO1_RS04340 (STO1_008400) lepA 849032..850855 (+) 1824 WP_007522109.1 translation elongation factor 4 -
  STO1_RS04345 (STO1_008410) - 851002..851625 (+) 624 WP_096422101.1 hypothetical protein -
  STO1_RS04350 (STO1_008420) dprA/cilB/dalA 851707..852555 (+) 849 WP_096422103.1 DNA-processing protein DprA Machinery gene
  STO1_RS04355 (STO1_008430) topA 852787..854874 (+) 2088 WP_057489171.1 type I DNA topoisomerase -
  STO1_RS04360 (STO1_008440) - 854981..855340 (+) 360 WP_001220350.1 YbaN family protein -
  STO1_RS04365 (STO1_008450) - 855434..856066 (+) 633 WP_000638773.1 copper homeostasis protein CutC -
  STO1_RS04370 (STO1_008460) - 856110..856766 (+) 657 WP_000461561.1 MmcQ/YjbR family DNA-binding protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31138.59 Da        Isoelectric Point: 5.1903

>NTDB_id=69056 STO1_RS04350 WP_096422103.1 851707..852555(+) (dprA/cilB/dalA) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAEISGCCNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQRVIQGLGNELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGTGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=69056 STO1_RS04350 WP_096422103.1 851707..852555(+) (dprA/cilB/dalA) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAGATCACAAACTATGAGATTTACAAATTGAGAAAAGCAGGGCTGACCAATCAACAGATTCTAACTGTTCTTGAATA
TGATGAGACTGTAGATCAGGAGCTCTTGCTGGGTGATATTGCAGAAATATCGGGATGCTGTAATCCTGCAGTTTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTCCAAAAATTTCCTTCCTTTTCTATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTGTTTTATAAAGGAAATCTAGACTTGTTAAAGTTTCC
GAAAGTTGCTGTTGTAGGGAGCCGTTCATGTTCTAGTCAGGGAGCAAAGTCGGTTCAGAGAGTCATCCAAGGTTTGGGAA
ACGAGTTGATCGTGGTCAGTGGCTTGGCTAAAGGAATTGATACAGCCGCCCATATGGCTGCACTCCAGAATGGAGGAAGA
ACGATTGCAGTGATTGGAACAGGATTGGATGTATTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGTACAGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGAAATCGTATCATAGCAG
GACTGTGTCGTGGGGTTATTGTAGCAGAGGCAAGGATGCGTTCGGGCAGTCTCATCACCTGTGAGCGTGCTATGGAGGAA
GGGCGCGATGTCTTTGCCATTCCAGGGAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTAATCCAAGAGGGAGC
AAAACTGGTCACCAGCGGTCAAGATGTGCTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A224A6N0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

90.78

100

0.908
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

90.426

100

0.904
  dprA/cilB/dalA Streptococcus pneumoniae D39

90.426

100

0.904
  dprA/cilB/dalA Streptococcus pneumoniae R6

90.426

100

0.904
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

90.426

100

0.904
  dprA/cilB/dalA Streptococcus mitis SK321

89.716

100

0.897
  dprA Streptococcus mutans UA159

60.357

99.291

0.599
  dprA Lactococcus lactis subsp. cremoris KW2

54.643

99.291

0.543
  dprA Vibrio campbellii strain DS40M4

36.655

99.645

0.365
  dprA Haemophilus influenzae Rd KW20

38.433

95.035

0.365

Multiple sequence alignment