Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ORP33_RS20640 Genome accession   NZ_CP113256
Coordinates   3997019..3998221 (-) Length   400 a.a.
NCBI ID   WP_003226941.1    Uniprot ID   -
Organism   Bacillus subtilis strain K1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3992019..4003221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORP33_RS20615 (ORP33_20190) - 3992953..3994419 (-) 1467 WP_119899992.1 sensor histidine kinase -
  ORP33_RS20620 (ORP33_20195) - 3994416..3995099 (-) 684 WP_024573086.1 response regulator transcription factor -
  ORP33_RS20625 (ORP33_20200) - 3995311..3996210 (+) 900 WP_225722168.1 PepSY domain-containing protein -
  ORP33_RS20630 (ORP33_20205) - 3996372..3996872 (+) 501 WP_003226943.1 PepSY domain-containing protein -
  ORP33_RS20635 - 3996869..3996998 (-) 130 Protein_4016 hypothetical protein -
  ORP33_RS20640 (ORP33_20210) htrA 3997019..3998221 (-) 1203 WP_003226941.1 serine protease HtrC Regulator
  ORP33_RS20645 (ORP33_20215) vicX 3998303..3999097 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  ORP33_RS20650 (ORP33_20220) walI 3999119..3999961 (-) 843 WP_029318542.1 WalRK two-component regulatory system regulator WalI -
  ORP33_RS20655 (ORP33_20225) walH 3999948..4001315 (-) 1368 WP_225722169.1 WalRK two-component regulatory system regulator WalH -
  ORP33_RS20660 (ORP33_20230) walK 4001305..4003140 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42707.47 Da        Isoelectric Point: 6.0098

>NTDB_id=690472 ORP33_RS20640 WP_003226941.1 3997019..3998221(-) (htrA) [Bacillus subtilis strain K1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
HVTNGAVVMGVDAFSPAGKAGLKELDVITGFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=690472 ORP33_RS20640 WP_003226941.1 3997019..3998221(-) (htrA) [Bacillus subtilis strain K1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTG
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGGATTGAGATGAAATCGCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
CATGTTACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGGATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(197-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

42.746

96.5

0.412
  htrA Streptococcus pneumoniae TIGR4

45.455

82.5

0.375
  htrA Streptococcus pneumoniae D39

45.455

82.5

0.375
  htrA Streptococcus pneumoniae Rx1

45.455

82.5

0.375
  htrA Streptococcus pneumoniae R6

45.455

82.5

0.375