Detailed information NTG0688036

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: M3N36_RS04860
• Genome accession: NZ_CP097251
• Coordinates: 938010..938846 (+)
• Length: 278 a.a.
• NCBI ID: WP_030127252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 933010..943846

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3N36_RS04830 (M3N36_04830)	-	933498..933932 (+)	435	WP_011017767.1	hypothetical protein	-
M3N36_RS04835 (M3N36_04835)	-	933982..934893 (-)	912	WP_011184516.1	diacylglycerol kinase family protein	-
M3N36_RS04840 (M3N36_04840)	-	935010..935660 (-)	651	WP_002984629.1	hemolysin III family protein	-
M3N36_RS04845 (M3N36_04845)	-	935657..936097 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
M3N36_RS04850 (M3N36_04850)	ylqF	936316..937164 (+)	849	WP_030127254.1	ribosome biogenesis GTPase YlqF	-
M3N36_RS04855 (M3N36_04855)	-	937154..937945 (+)	792	WP_030127253.1	ribonuclease HII	-
M3N36_RS04860 (M3N36_04860)	dprA	938010..938846 (+)	837	WP_030127252.1	DNA-processing protein DprA	Machinery gene
M3N36_RS04865 (M3N36_04865)	topA	938953..941082 (+)	2130	WP_030127251.1	type I DNA topoisomerase	-
M3N36_RS04870 (M3N36_04870)	trmFO	941217..942563 (+)	1347	WP_030127250.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31087.09 Da
• Isoelectric Point: 9.2565

>NTDB_id=688036 M3N36_RS04860 WP_030127252.1 938010..938846(+) (dprA) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSNTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=688036 M3N36_RS04860 WP_030127252.1 938010..938846(+) (dprA) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCAATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367