Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SNAG_RS04895 Genome accession   NZ_AP017652
Coordinates   926358..927062 (+) Length   234 a.a.
NCBI ID   WP_096407079.1    Uniprot ID   A0A1E1GAB8
Organism   Streptococcus sp. NPS 308     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 921358..932062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS04870 (SNAG_0951) - 921655..922326 (+) 672 WP_000151560.1 GTP pyrophosphokinase family protein -
  SNAG_RS04875 (SNAG_0952) - 922310..923128 (+) 819 WP_096407068.1 NAD kinase -
  SNAG_RS04880 (SNAG_0953) - 923125..924021 (+) 897 WP_096407070.1 RluA family pseudouridine synthase -
  SNAG_RS04885 (SNAG_0954) pta 924065..925039 (+) 975 WP_096407073.1 phosphate acetyltransferase -
  SNAG_RS04890 (SNAG_0955) mutY 925122..926300 (+) 1179 WP_096407076.1 A/G-specific adenine glycosylase -
  SNAG_RS04895 (SNAG_0956) micA 926358..927062 (+) 705 WP_096407079.1 response regulator YycF Regulator
  SNAG_RS04900 (SNAG_0957) micB 927055..928404 (+) 1350 WP_096407081.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SNAG_RS04905 (SNAG_0958) vicX 928406..929215 (+) 810 WP_096407084.1 MBL fold metallo-hydrolase Regulator
  SNAG_RS04910 (SNAG_0959) - 929310..930083 (+) 774 WP_096407086.1 ion transporter -
  SNAG_RS04915 (SNAG_0960) - 930121..930468 (-) 348 WP_096407089.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 27049.95 Da        Isoelectric Point: 4.6834

>NTDB_id=68347 SNAG_RS04895 WP_096407079.1 926358..927062(+) (micA) [Streptococcus sp. NPS 308]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTELIAVDNQEEDTKLQSLQIRDLEILPDAYVAKKYGEELDLT
HREFELLHHLASHLGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=68347 SNAG_RS04895 WP_096407079.1 926358..927062(+) (micA) [Streptococcus sp. NPS 308]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTCAATATGACCAAAGAAGGCTACGA
AGTTGTAACAGCCTTCAACGGTCGTGAGGCAATCGAGCTATTTGAAGCCGAGCAACCCGACATTATTATCCTAGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGCAAGACCAGTAGTGTTCCTATCATTATGCTCTCAGCT
AAGGATAGCGAGTTTGACAAGGTTATCGGTTTGGAACTAGGTGCAGACGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAGGCGCGTGTCAAGGCCCTTCTTCGTCGCACTGAGCTAATCGCAGTGGATAACCAAGAAGAAGATACTAAATTAC
AAAGTCTTCAAATTAGAGATTTAGAGATTCTTCCAGATGCTTATGTAGCCAAAAAATATGGAGAAGAATTGGATTTAACT
CACAGAGAATTTGAGTTGTTGCATCACTTAGCTTCTCATCTAGGTCAAGTTATTACCCGTGAACATCTCCTTGAGACGGT
TTGGGGTTATGATTATTTTGGTGATGTTCGTACTGTCGATGTTACCATTAGACGTCTACGTGAGAAGATTGAAGACACAC
CAAGTAGACCTGAATATATCTTAACTCGTCGTGGTGTGGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GAB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.416

99.573

0.91
  vicR Streptococcus mutans UA159

78.723

100

0.791
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.217

98.291

0.444
  covR Streptococcus salivarius strain HSISS4

44.348

98.291

0.436
  scnR Streptococcus mutans UA159

37.069

99.145

0.368

Multiple sequence alignment