Detailed information NTG0068346

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SNAG_RS04545
• Genome accession: NZ_AP017652
• Coordinates: 854511..855359 (+)
• Length: 282 a.a.
• NCBI ID: WP_096406933.1
• Uniprot ID: A0A1E1GAG9
• Organism: Streptococcus sp. NPS 308
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 849511..860359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SNAG_RS04525 (SNAG_0882)	-	849607..850038 (+)	432	WP_001034393.1	arginine repressor	-
SNAG_RS04530 (SNAG_0883)	recN	850045..851712 (+)	1668	WP_000923561.1	DNA repair protein RecN	-
SNAG_RS04535 (SNAG_0884)	-	851713..852441 (+)	729	WP_096406931.1	metallophosphoesterase	-
SNAG_RS04540 (SNAG_0885)	lepA	852520..854343 (+)	1824	WP_001047195.1	translation elongation factor 4	-
SNAG_RS04545 (SNAG_0886)	dprA/cilB/dalA	854511..855359 (+)	849	WP_096406933.1	DNA-processing protein DprA	Machinery gene
SNAG_RS04550 (SNAG_0887)	topA	855476..857563 (+)	2088	WP_096406936.1	type I DNA topoisomerase	-
SNAG_RS04555 (SNAG_0888)	-	857670..858029 (+)	360	WP_096406939.1	YbaN family protein	-
SNAG_RS04560 (SNAG_0889)	-	858122..858754 (+)	633	WP_096406941.1	copper homeostasis protein CutC	-
SNAG_RS04565 (SNAG_0890)	-	858798..859454 (+)	657	WP_096406944.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31368.92 Da
• Isoelectric Point: 4.9548

>NTDB_id=68346 SNAG_RS04545 WP_096406933.1 854511..855359(+) (dprA/cilB/dalA) [Streptococcus sp. NPS 308]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVEQELLLGDIAEISGCRNPAVFMERYFQIDDVQLEKEFQKFPSFSILDEC
YPWDLSEIYDPPALLFYKGNLDLLKFPKVALVGSRSCSSQGAKSVQKIIQGLENELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRANKRLQEYIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGDILDGHSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=68346 SNAG_RS04545 WP_096406933.1 854511..855359(+) (dprA/cilB/dalA) [Streptococcus sp. NPS 308]
ATGAAAATTACAAACTATGAGATTTACAAATTAAGAAAAGCAGGCTTGACCAATCAACAGATTTTAACTGTTCTTGAATA
TGACGAGACTGTAGAGCAGGAACTTTTGTTAGGAGATATTGCTGAAATCTCTGGTTGCCGCAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGTGCAGTTGGAGAAGGAGTTTCAAAAATTCCCATCTTTCTCGATTCTAGACGAGTGT
TATCCTTGGGATCTGAGTGAGATTTATGACCCTCCAGCTCTTTTGTTTTACAAAGGGAATCTGGATTTATTGAAATTTCC
CAAGGTTGCTCTTGTAGGGAGTCGTTCTTGTTCCAGCCAAGGTGCTAAGTCGGTCCAGAAAATTATCCAAGGTTTAGAAA
ACGAGTTAATCGTGGTTAGTGGCTTGGCCAAAGGAATCGATACCGCTGCCCATATGGCTGCGCTCCAGAATGGAGGGAGA
ACGATTGCTGTAATCGGAACAGGATTGGATGTTTTTTATCCACGTGCTAACAAACGCTTGCAGGAGTACATTGGAAATCA
TCATCTAGTGCTAAGTGAGTACGGTCCAGGTGAAGAACCCTTGAAATTCCATTTTCCAGCCCGTAATCGTATCATTGCAG
GATTGTGTCGTGGAGTTATTGTGGCAGAGGCAAGGATGCGTTCAGGAAGTCTCATTACCTGTGAACGTGCCATGGAGGAA
GGACGCGATGTTTTTGCTATTCCAGGGGACATTCTTGATGGCCATTCAGATGGTTGCCACCACTTGATCCAAGAGGGAGC
AAAACTGGTCACAAGTGGTCAAGATGTGTTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

3D structure

• AlphaFold DB: A0A1E1GAG9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	90.426	100	0.904
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	90.071	100	0.901
dprA/cilB/dalA	Streptococcus pneumoniae D39	90.071	100	0.901
dprA/cilB/dalA	Streptococcus pneumoniae R6	90.071	100	0.901
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	90.071	100	0.901
dprA/cilB/dalA	Streptococcus mitis SK321	90.071	100	0.901
dprA	Streptococcus mutans UA159	61.071	99.291	0.606
dprA	Lactococcus lactis subsp. cremoris KW2	55	99.291	0.546
dprA	Acinetobacter baylyi ADP1	39.163	93.262	0.365