Detailed information
Bioinformatically predicted
Overview
| Name | comB | Type | Regulator |
| Locus tag | SNAG_RS00480 | Genome accession | NZ_AP017652 |
| Coordinates | 74949..76298 (+) | Length | 449 a.a. |
| NCBI ID | WP_096405764.1 | Uniprot ID | A0A1E1G8C4 |
| Organism | Streptococcus sp. NPS 308 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 12172..86382 | 74949..76298 | within | 0 |
Gene organization within MGE regions
Location: 12172..86382
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SNAG_RS00060 (SNAG_0013) | ftsH | 12172..14130 (+) | 1959 | WP_000744576.1 | ATP-dependent zinc metalloprotease FtsH | - |
| SNAG_RS00065 | - | 14185..14415 (+) | 231 | Protein_13 | 23S rRNA (uracil-5-)-methyltransferase RumA | - |
| SNAG_RS09850 (SNAG_0021) | comW | 20457..20690 (+) | 234 | WP_096405660.1 | sigma(X)-activator ComW | - |
| SNAG_RS00105 (SNAG_0022) | - | 20936..22222 (+) | 1287 | WP_096408773.1 | adenylosuccinate synthase | - |
| SNAG_RS00110 (SNAG_0023) | tadA | 22424..22891 (+) | 468 | WP_096405661.1 | tRNA adenosine(34) deaminase TadA | - |
| SNAG_RS00120 (SNAG_0024) | - | 23100..24242 (-) | 1143 | WP_096405663.1 | site-specific integrase | - |
| SNAG_RS00125 (SNAG_0025) | - | 24368..24832 (-) | 465 | WP_096405665.1 | hypothetical protein | - |
| SNAG_RS00130 (SNAG_0026) | - | 24858..25595 (-) | 738 | WP_096405666.1 | XRE family transcriptional regulator | - |
| SNAG_RS00135 (SNAG_0027) | - | 25756..25968 (+) | 213 | WP_096405668.1 | helix-turn-helix transcriptional regulator | - |
| SNAG_RS09790 (SNAG_0028) | - | 26023..26175 (+) | 153 | WP_172842362.1 | hypothetical protein | - |
| SNAG_RS00140 (SNAG_0029) | - | 26129..26776 (-) | 648 | WP_096405670.1 | hypothetical protein | - |
| SNAG_RS00150 (SNAG_0031) | - | 27125..27397 (+) | 273 | WP_054380428.1 | hypothetical protein | - |
| SNAG_RS00160 (SNAG_0032) | - | 27579..27878 (+) | 300 | WP_096405673.1 | hypothetical protein | - |
| SNAG_RS00165 (SNAG_0033) | - | 27893..29173 (+) | 1281 | WP_096405675.1 | AAA family ATPase | - |
| SNAG_RS00170 (SNAG_0034) | - | 29177..30304 (+) | 1128 | WP_096405677.1 | ATP-binding protein | - |
| SNAG_RS00175 (SNAG_0035) | - | 30368..30919 (+) | 552 | WP_096405678.1 | hypothetical protein | - |
| SNAG_RS00180 (SNAG_0036) | - | 30930..32513 (+) | 1584 | WP_096405680.1 | DEAD/DEAH box helicase | - |
| SNAG_RS00185 (SNAG_0037) | - | 32529..34814 (+) | 2286 | WP_096405682.1 | AAA family ATPase | - |
| SNAG_RS00190 (SNAG_0038) | - | 35046..35447 (+) | 402 | WP_096405683.1 | RusA family crossover junction endodeoxyribonuclease | - |
| SNAG_RS00195 (SNAG_0039) | - | 35444..35659 (+) | 216 | WP_096405685.1 | hypothetical protein | - |
| SNAG_RS00200 (SNAG_0040) | - | 35663..35851 (+) | 189 | WP_096405687.1 | hypothetical protein | - |
| SNAG_RS00205 (SNAG_0041) | - | 35844..36533 (+) | 690 | WP_096405689.1 | DUF1642 domain-containing protein | - |
| SNAG_RS00210 (SNAG_0042) | - | 36530..37054 (+) | 525 | WP_096405690.1 | hypothetical protein | - |
| SNAG_RS00215 (SNAG_0043) | - | 37067..37585 (+) | 519 | WP_231906642.1 | DUF1642 domain-containing protein | - |
| SNAG_RS00220 (SNAG_0044) | - | 37750..38088 (+) | 339 | WP_096405692.1 | hypothetical protein | - |
| SNAG_RS00225 (SNAG_0045) | - | 38090..38350 (+) | 261 | WP_096405693.1 | DUF1372 family protein | - |
| SNAG_RS00230 (SNAG_0046) | - | 38347..38838 (+) | 492 | WP_096405695.1 | MazG-like family protein | - |
| SNAG_RS00235 (SNAG_0047) | - | 38835..39224 (+) | 390 | WP_096405696.1 | YopX family protein | - |
| SNAG_RS00240 (SNAG_0048) | - | 39221..39469 (+) | 249 | WP_096405698.1 | hypothetical protein | - |
| SNAG_RS00245 (SNAG_0049) | - | 39456..39692 (+) | 237 | WP_231906643.1 | helix-turn-helix transcriptional regulator | - |
| SNAG_RS00250 (SNAG_0050) | - | 39796..40122 (+) | 327 | WP_231906644.1 | DUF1492 domain-containing protein | - |
| SNAG_RS00260 (SNAG_0052) | - | 41316..41810 (+) | 495 | WP_096405703.1 | terminase small subunit | - |
| SNAG_RS00265 (SNAG_0053) | - | 41800..43014 (+) | 1215 | WP_096405705.1 | PBSX family phage terminase large subunit | - |
| SNAG_RS00270 (SNAG_0054) | - | 43026..44438 (+) | 1413 | WP_096405706.1 | phage portal protein | - |
| SNAG_RS00275 (SNAG_0055) | - | 44401..46422 (+) | 2022 | WP_096405708.1 | minor capsid protein | - |
| SNAG_RS00280 (SNAG_0056) | - | 46435..46650 (+) | 216 | WP_096405709.1 | hypothetical protein | - |
| SNAG_RS09725 | - | 47134..47301 (+) | 168 | WP_157740105.1 | hypothetical protein | - |
| SNAG_RS00290 (SNAG_0059) | - | 47320..47532 (+) | 213 | WP_096405711.1 | hypothetical protein | - |
| SNAG_RS00295 (SNAG_0060) | - | 47643..48155 (+) | 513 | WP_096405713.1 | DUF4355 domain-containing protein | - |
| SNAG_RS00300 (SNAG_0061) | - | 48183..49199 (+) | 1017 | WP_096405714.1 | carbohydrate-binding protein | - |
| SNAG_RS00305 (SNAG_0062) | - | 49210..49413 (+) | 204 | WP_096405716.1 | hypothetical protein | - |
| SNAG_RS00310 (SNAG_0063) | - | 49422..49733 (+) | 312 | WP_096405717.1 | phage head-tail connector protein | - |
| SNAG_RS00315 (SNAG_0064) | - | 49714..50052 (+) | 339 | WP_096405719.1 | hypothetical protein | - |
| SNAG_RS00320 (SNAG_0065) | - | 50027..50539 (+) | 513 | WP_096405720.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| SNAG_RS00325 (SNAG_0066) | - | 50536..50904 (+) | 369 | WP_096405722.1 | hypothetical protein | - |
| SNAG_RS00330 (SNAG_0067) | - | 50908..51321 (+) | 414 | WP_096405724.1 | phage tail tube protein | - |
| SNAG_RS00335 (SNAG_0068) | - | 51325..51717 (+) | 393 | WP_096405726.1 | DUF6096 family protein | - |
| SNAG_RS00340 (SNAG_0069) | - | 51768..52109 (+) | 342 | WP_096405728.1 | hypothetical protein | - |
| SNAG_RS00345 (SNAG_0070) | - | 52110..55349 (+) | 3240 | WP_096405729.1 | hypothetical protein | - |
| SNAG_RS00350 (SNAG_0071) | - | 55361..55711 (+) | 351 | WP_096405731.1 | DUF6711 family protein | - |
| SNAG_RS00355 (SNAG_0072) | - | 55720..59001 (+) | 3282 | WP_172842363.1 | tail fiber domain-containing protein | - |
| SNAG_RS00360 (SNAG_0073) | - | 58998..59207 (+) | 210 | WP_096405733.1 | hypothetical protein | - |
| SNAG_RS00365 (SNAG_0074) | - | 59197..59784 (+) | 588 | WP_096405735.1 | hypothetical protein | - |
| SNAG_RS00370 (SNAG_0075) | - | 59795..60235 (+) | 441 | WP_096405737.1 | hypothetical protein | - |
| SNAG_RS00375 (SNAG_0076) | - | 60219..60551 (+) | 333 | WP_096405739.1 | phage holin | - |
| SNAG_RS00380 (SNAG_0077) | - | 60554..61420 (+) | 867 | WP_096405741.1 | CHAP domain-containing protein | - |
| SNAG_RS00390 (SNAG_0078) | - | 61750..62022 (+) | 273 | WP_096405745.1 | hypothetical protein | - |
| SNAG_RS00395 (SNAG_0079) | - | 62196..62639 (+) | 444 | WP_096405746.1 | dUTP diphosphatase | - |
| SNAG_RS00400 (SNAG_0080) | - | 62641..63156 (+) | 516 | WP_172842364.1 | histidine phosphatase family protein | - |
| SNAG_RS00405 (SNAG_0081) | radA | 63167..64531 (+) | 1365 | WP_172842411.1 | DNA repair protein RadA | Machinery gene |
| SNAG_RS00410 (SNAG_0082) | - | 64604..65098 (+) | 495 | WP_172842365.1 | carbonic anhydrase | - |
| SNAG_RS00415 (SNAG_0083) | - | 65313..66281 (+) | 969 | WP_000010178.1 | ribose-phosphate diphosphokinase | - |
| SNAG_RS00420 (SNAG_0084) | - | 66402..66839 (+) | 438 | WP_049538209.1 | CoA-binding protein | - |
| SNAG_RS00425 (SNAG_0085) | - | 66866..67876 (-) | 1011 | WP_096405753.1 | YeiH family protein | - |
| SNAG_RS00430 (SNAG_0086) | - | 68027..69196 (+) | 1170 | WP_096405755.1 | pyridoxal phosphate-dependent aminotransferase | - |
| SNAG_RS00435 (SNAG_0087) | recO | 69193..69963 (+) | 771 | WP_096405757.1 | DNA repair protein RecO | - |
| SNAG_RS00440 (SNAG_0088) | plsX | 69960..70952 (+) | 993 | WP_096405758.1 | phosphate acyltransferase PlsX | - |
| SNAG_RS00445 (SNAG_0089) | - | 70956..71192 (+) | 237 | WP_000182270.1 | acyl carrier protein | - |
| SNAG_RS00450 (SNAG_0090) | - | 71639..71827 (+) | 189 | WP_000180817.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| SNAG_RS00455 (SNAG_0091) | - | 71845..72012 (+) | 168 | WP_096405760.1 | class IIb bacteriocin, lactobin A/cerein 7B family | - |
| SNAG_RS00460 (SNAG_0092) | - | 72022..72210 (+) | 189 | WP_049519176.1 | hypothetical protein | - |
| SNAG_RS09855 (SNAG_0093) | - | 72235..72417 (+) | 183 | WP_000869799.1 | hypothetical protein | - |
| SNAG_RS09860 (SNAG_0094) | - | 72419..72613 (+) | 195 | WP_084938708.1 | hypothetical protein | - |
| SNAG_RS00475 (SNAG_0095) | comA | 72777..74936 (+) | 2160 | WP_096405762.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| SNAG_RS00480 (SNAG_0096) | comB | 74949..76298 (+) | 1350 | WP_096405764.1 | competence pheromone export protein ComB | Regulator |
| SNAG_RS00485 (SNAG_0097) | purC | 76467..77174 (+) | 708 | WP_172842366.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| SNAG_RS09985 | - | 77251..77319 (+) | 69 | Protein_88 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| SNAG_RS00495 (SNAG_0098) | - | 77386..81111 (+) | 3726 | WP_096405768.1 | phosphoribosylformylglycinamidine synthase | - |
| SNAG_RS00500 (SNAG_0099) | purF | 81273..82715 (+) | 1443 | WP_096405770.1 | amidophosphoribosyltransferase | - |
| SNAG_RS00505 (SNAG_0100) | purM | 82754..83776 (+) | 1023 | WP_096408784.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| SNAG_RS00510 (SNAG_0101) | purN | 83773..84324 (+) | 552 | WP_096405771.1 | phosphoribosylglycinamide formyltransferase | - |
| SNAG_RS00515 (SNAG_0102) | - | 84369..84833 (+) | 465 | WP_096405773.1 | GNAT family N-acetyltransferase | - |
| SNAG_RS00520 (SNAG_0103) | purH | 84835..86382 (+) | 1548 | WP_096405775.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 49771.76 Da Isoelectric Point: 5.1426
>NTDB_id=68317 SNAG_RS00480 WP_096405764.1 74949..76298(+) (comB) [Streptococcus sp. NPS 308]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSARATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIETGAQLDSQNAAYSFYQTYKNQAGEDPQAKSQVIAQVDAQIT
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLTSKDVARLKVGDSVRFTTSKDGNKELVLVSAITNIDATATKTEK
GNFFKIEVETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSARATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIETGAQLDSQNAAYSFYQTYKNQAGEDPQAKSQVIAQVDAQIT
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLTSKDVARLKVGDSVRFTTSKDGNKELVLVSAITNIDATATKTEK
GNFFKIEVETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE
Nucleotide
Download Length: 1350 bp
>NTDB_id=68317 SNAG_RS00480 WP_096405764.1 74949..76298(+) (comB) [Streptococcus sp. NPS 308]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCCCTTCTGCTCGTATTTCTGCTAGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTGCCAGAGCAACTGTCG
AACCTAGTCGAATAATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAATTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGGGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAAGCAG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGAAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCTTCTCAAAATGCAGCCGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATTCGAGATTACAAAACAGCTAAGTCGGCGATTGAAACAGGAGCTCAACTAGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACTTATAAAAACCAAGCTGGAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATTACC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTTGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGATAAGGGAAAAATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACTCTGCTAGCCCAGCTCTATCCATCCTTGGAAAAAGA
AGGTAAAACTAAACTCACGGCTTATCTTACTTCAAAAGATGTTGCAAGGCTCAAGGTCGGTGATTCTGTCCGTTTCACTA
CAAGCAAGGATGGTAATAAAGAGCTCGTTCTTGTTTCTGCGATTACGAATATTGACGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGTGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGACG
TTTGACGCTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCCCTTCTGCTCGTATTTCTGCTAGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTGCCAGAGCAACTGTCG
AACCTAGTCGAATAATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAATTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGGGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAAGCAG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGAAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCTTCTCAAAATGCAGCCGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATTCGAGATTACAAAACAGCTAAGTCGGCGATTGAAACAGGAGCTCAACTAGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACTTATAAAAACCAAGCTGGAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATTACC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTTGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGATAAGGGAAAAATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACTCTGCTAGCCCAGCTCTATCCATCCTTGGAAAAAGA
AGGTAAAACTAAACTCACGGCTTATCTTACTTCAAAAGATGTTGCAAGGCTCAAGGTCGGTGATTCTGTCCGTTTCACTA
CAAGCAAGGATGGTAATAAAGAGCTCGTTCTTGTTTCTGCGATTACGAATATTGACGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGTGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGACG
TTTGACGCTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB | Streptococcus mitis SK321 |
80.846 |
100 |
0.808 |
| comB | Streptococcus pneumoniae Rx1 |
80.401 |
100 |
0.804 |
| comB | Streptococcus pneumoniae D39 |
80.401 |
100 |
0.804 |
| comB | Streptococcus pneumoniae R6 |
80.401 |
100 |
0.804 |
| comB | Streptococcus pneumoniae TIGR4 |
80.178 |
100 |
0.802 |
| comB | Streptococcus mitis NCTC 12261 |
79.287 |
100 |
0.793 |
| comB | Streptococcus gordonii str. Challis substr. CH1 |
54.667 |
100 |
0.548 |