Detailed information NTG0676986

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: MU520_RS00090
• Genome accession: NZ_CP095463
• Coordinates: 19060..20256 (-)
• Length: 398 a.a.
• NCBI ID: WP_012028059.1
• Uniprot ID: D5AF49
• Organism: Streptococcus suis strain TJS56
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 14060..25256

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MU520_RS00065	-	14183..14386 (-)	204	WP_011922523.1	DUF951 family protein	-
MU520_RS00070	-	14396..15277 (-)	882	WP_011921629.1	diacylglycerol kinase family protein	-
MU520_RS00075	dnaN	15369..16505 (-)	1137	WP_004194538.1	DNA polymerase III subunit beta	-
MU520_RS00080	dnaA	16659..18032 (-)	1374	WP_011921628.1	chromosomal replication initiator protein DnaA	-
MU520_RS00085	spo0J	18235..18999 (-)	765	WP_012775418.1	ParB/RepB/Spo0J family partition protein	Regulator
MU520_RS00090	htrA	19060..20256 (-)	1197	WP_012028059.1	trypsin-like peptidase domain-containing protein	Regulator
MU520_RS00095	rlmH	20430..20909 (+)	480	WP_012028058.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
MU520_RS00100	-	20934..21617 (+)	684	WP_012775416.1	YoaK family protein	-
MU520_RS00120	-	22018..24597 (-)	2580	WP_012028056.1	YfhO family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41866.92 Da
• Isoelectric Point: 4.6543

>NTDB_id=676986 MU520_RS00090 WP_012028059.1 19060..20256(-) (htrA) [Streptococcus suis strain TJS56]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=676986 MU520_RS00090 WP_012028059.1 19060..20256(-) (htrA) [Streptococcus suis strain TJS56]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTGTCAGCCTCTTTCTTCCAGCCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAATATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

• PDZ domain (PDZ_2) (293-389)

3D structure

• AlphaFold DB: D5AF49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.194	99.749	0.59
htrA	Streptococcus gordonii str. Challis substr. CH1	58.987	99.246	0.585
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565