Detailed information NTG0675862

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: MUY23_RS10910
• Genome accession: NZ_CP095162
• Coordinates: 2215449..2216645 (-)
• Length: 398 a.a.
• NCBI ID: WP_009911075.1
• Uniprot ID: G7SHV4
• Organism: Streptococcus suis strain TJS75
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2210449..2221645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUY23_RS10890	-	2210633..2211514 (-)	882	WP_004194540.1	diacylglycerol kinase family protein	-
MUY23_RS10895	dnaN	2211758..2212894 (-)	1137	WP_004194538.1	DNA polymerase III subunit beta	-
MUY23_RS10900	dnaA	2213048..2214421 (-)	1374	WP_004194536.1	chromosomal replication initiator protein DnaA	-
MUY23_RS10905	spo0J	2214624..2215388 (-)	765	WP_004194534.1	ParB/RepB/Spo0J family partition protein	Regulator
MUY23_RS10910	htrA	2215449..2216645 (-)	1197	WP_009911075.1	trypsin-like peptidase domain-containing protein	Regulator
MUY23_RS10915	rlmH	2216819..2217298 (+)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
MUY23_RS10920	-	2217323..2218006 (+)	684	WP_004194526.1	YoaK family protein	-
MUY23_RS10940	-	2218407..2220986 (-)	2580	WP_004194524.1	YfhO family protein	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41818.83 Da
• Isoelectric Point: 4.6655

>NTDB_id=675862 MUY23_RS10910 WP_009911075.1 2215449..2216645(-) (htrA) [Streptococcus suis strain TJS75]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPRVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=675862 MUY23_RS10910 WP_009911075.1 2215449..2216645(-) (htrA) [Streptococcus suis strain TJS75]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACGGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCTACTACAAAGGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCTGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCCAATACAGTTACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACTAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGGCTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

3D structure

• AlphaFold DB: G7SHV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.446	99.749	0.593
htrA	Streptococcus gordonii str. Challis substr. CH1	59.494	99.246	0.59
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565