Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   MP619_RS05565 Genome accession   NZ_CP095081
Coordinates   1067483..1068157 (+) Length   224 a.a.
NCBI ID   WP_129555678.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1062483..1073157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS05550 (MP619_05530) pstB 1063052..1063810 (+) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -
  MP619_RS05555 (MP619_05535) phoU 1063888..1064541 (+) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  MP619_RS05560 (MP619_05540) - 1064742..1067279 (+) 2538 WP_129555677.1 M1 family metallopeptidase -
  MP619_RS05565 (MP619_05545) ciaR 1067483..1068157 (+) 675 WP_129555678.1 response regulator transcription factor Regulator
  MP619_RS05570 (MP619_05550) ciaH 1068150..1069460 (+) 1311 WP_129555679.1 HAMP domain-containing sensor histidine kinase Regulator
  MP619_RS05575 (MP619_05555) rpsT 1069618..1069866 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  MP619_RS05580 (MP619_05560) coaA 1069920..1070840 (-) 921 WP_129555680.1 type I pantothenate kinase -
  MP619_RS05585 (MP619_05565) - 1071109..1071708 (+) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  MP619_RS05590 (MP619_05570) - 1071695..1072972 (+) 1278 WP_129555681.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25573.52 Da        Isoelectric Point: 4.4123

>NTDB_id=675095 MP619_RS05565 WP_129555678.1 1067483..1068157(+) (ciaR) [Streptococcus dysgalactiae strain WJ001]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGQPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=675095 MP619_RS05565 WP_129555678.1 1067483..1068157(+) (ciaR) [Streptococcus dysgalactiae strain WJ001]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGCGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAACGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCAGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(5-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

35.443

100

0.375