Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   MP619_RS05570 Genome accession   NZ_CP095081
Coordinates   1068150..1069460 (+) Length   436 a.a.
NCBI ID   WP_129555679.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1063150..1074460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS05555 (MP619_05535) phoU 1063888..1064541 (+) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  MP619_RS05560 (MP619_05540) - 1064742..1067279 (+) 2538 WP_129555677.1 M1 family metallopeptidase -
  MP619_RS05565 (MP619_05545) ciaR 1067483..1068157 (+) 675 WP_129555678.1 response regulator transcription factor Regulator
  MP619_RS05570 (MP619_05550) ciaH 1068150..1069460 (+) 1311 WP_129555679.1 HAMP domain-containing sensor histidine kinase Regulator
  MP619_RS05575 (MP619_05555) rpsT 1069618..1069866 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  MP619_RS05580 (MP619_05560) coaA 1069920..1070840 (-) 921 WP_129555680.1 type I pantothenate kinase -
  MP619_RS05585 (MP619_05565) - 1071109..1071708 (+) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  MP619_RS05590 (MP619_05570) - 1071695..1072972 (+) 1278 WP_129555681.1 pyrimidine-nucleoside phosphorylase -
  MP619_RS05595 (MP619_05575) deoC 1072988..1073650 (+) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  MP619_RS05600 (MP619_05580) - 1073637..1074026 (+) 390 WP_022554672.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49922.49 Da        Isoelectric Point: 8.2375

>NTDB_id=675096 MP619_RS05570 WP_129555679.1 1068150..1069460(+) (ciaH) [Streptococcus dysgalactiae strain WJ001]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=675096 MP619_RS05570 WP_129555679.1 1068150..1069460(+) (ciaH) [Streptococcus dysgalactiae strain WJ001]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGCAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGTACAATTTTGAATTCCTTTGATGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACTATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTAGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACTCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.124

100

0.583
  ciaH Streptococcus pneumoniae Rx1

51.37

100

0.516
  ciaH Streptococcus pneumoniae D39

51.37

100

0.516
  ciaH Streptococcus pneumoniae R6

51.37

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.37

100

0.516