Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   MUB28_RS07285 Genome accession   NZ_CP094945
Coordinates   1422607..1423302 (-) Length   231 a.a.
NCBI ID   WP_248857295.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain VHProbi R08     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1417607..1428302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUB28_RS07270 (MUB28_07270) - 1418418..1418963 (-) 546 WP_014608611.1 GNAT family N-acetyltransferase -
  MUB28_RS07275 (MUB28_07275) - 1419029..1420291 (-) 1263 WP_014608612.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  MUB28_RS07280 (MUB28_07280) - 1420377..1422617 (-) 2241 WP_014727657.1 DNA internalization-related competence protein ComEC/Rec2 -
  MUB28_RS07285 (MUB28_07285) comEA 1422607..1423302 (-) 696 WP_248857295.1 helix-hairpin-helix domain-containing protein Machinery gene
  MUB28_RS07290 (MUB28_07290) - 1423410..1424165 (-) 756 WP_002948862.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  MUB28_RS07295 (MUB28_07295) - 1424365..1424898 (+) 534 WP_014608615.1 polysaccharide deacetylase family protein -
  MUB28_RS07300 (MUB28_07300) - 1425007..1425156 (+) 150 WP_014608616.1 polysaccharide deacetylase -
  MUB28_RS07305 (MUB28_07305) - 1425206..1425970 (+) 765 WP_014608617.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  MUB28_RS07310 (MUB28_07310) - 1425974..1426243 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24501.46 Da        Isoelectric Point: 4.6300

>NTDB_id=674421 MUB28_RS07285 WP_248857295.1 1422607..1423302(-) (comEA) [Streptococcus thermophilus strain VHProbi R08]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGSSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQISDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=674421 MUB28_RS07285 WP_248857295.1 1422607..1423302(-) (comEA) [Streptococcus thermophilus strain VHProbi R08]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAGCAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAAGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGATCTCTGATAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.268

100

0.983
  comEA/celA/cilE Streptococcus mitis SK321

39.912

98.701

0.394
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372