Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   MP387_RS04330 Genome accession   NZ_CP094226
Coordinates   880602..881309 (+) Length   235 a.a.
NCBI ID   WP_000722058.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 875602..886309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS04305 (MP387_04305) - 875900..876571 (+) 672 WP_000151555.1 GTP pyrophosphokinase family protein -
  MP387_RS04310 (MP387_04310) - 876555..877373 (+) 819 WP_061413985.1 NAD kinase -
  MP387_RS04315 (MP387_04315) - 877370..878266 (+) 897 WP_242747939.1 RluA family pseudouridine synthase -
  MP387_RS04320 (MP387_04320) pta 878310..879284 (+) 975 WP_242747941.1 phosphate acetyltransferase -
  MP387_RS04325 (MP387_04325) mutY 879367..880545 (+) 1179 WP_242747943.1 A/G-specific adenine glycosylase -
  MP387_RS04330 (MP387_04330) micA 880602..881309 (+) 708 WP_000722058.1 response regulator YycF Regulator
  MP387_RS04335 (MP387_04335) micB 881302..882651 (+) 1350 WP_061413994.1 cell wall metabolism sensor histidine kinase VicK Regulator
  MP387_RS04340 (MP387_04340) vicX 882653..883462 (+) 810 WP_242747945.1 MBL fold metallo-hydrolase Regulator
  MP387_RS04345 (MP387_04345) - 883550..884350 (+) 801 Protein_807 ion transporter -
  MP387_RS04350 (MP387_04350) - 884360..884707 (-) 348 WP_242747947.1 thioredoxin -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=668103 MP387_RS04330 WP_000722058.1 880602..881309(+) (micA) [Streptococcus oralis strain 1648]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=668103 MP387_RS04330 WP_000722058.1 880602..881309(+) (micA) [Streptococcus oralis strain 1648]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTCGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCTGAGCAACCGGATATTATTATCCTCGACTTGA
TGCTACCTGAAATAGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCGATTATCATGCTATCAGCT
AAGGATAGCGAATTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAGGCTCGTGTCAAGGCTCTGCTTCGTCGTACAGACTTGGTTTCTGTGGATAGCCAAGAGTCTGATGAGAAGAAGA
CCCAGCCTTTACAAATTGGTGATTTGGAAATCGTTCCAGATGCTTACGTGGCTAAGAAATATGGTGAGGAGTTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCGTCTCATATTGGACAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACTGTGGACGTGACCATTAGACGATTGCGTGAAAAGATCGAAGACA
CACCAAGCCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment