Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   MP387_RS00195 Genome accession   NZ_CP094226
Coordinates   35022..36371 (+) Length   449 a.a.
NCBI ID   WP_242746691.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 30022..41371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS00165 (MP387_00165) plsX 30409..31401 (+) 993 WP_227232162.1 phosphate acyltransferase PlsX -
  MP387_RS00170 (MP387_00170) - 31407..31643 (+) 237 WP_000136435.1 acyl carrier protein -
  MP387_RS00175 (MP387_00175) - 31958..32134 (+) 177 WP_000180837.1 hypothetical protein -
  MP387_RS00180 (MP387_00180) - 32147..32338 (+) 192 WP_083321223.1 bacteriocin immunity protein -
  MP387_RS00185 (MP387_00185) - 32367..32537 (+) 171 WP_070837635.1 H354_08695 family bacteriocin-like peptide -
  MP387_RS00190 (MP387_00190) comA 32856..35009 (+) 2154 WP_242746689.1 peptide cleavage/export ABC transporter ComA Regulator
  MP387_RS00195 (MP387_00195) comB 35022..36371 (+) 1350 WP_242746691.1 competence pheromone export protein ComB Regulator
  MP387_RS00200 (MP387_00200) purC 36540..37247 (+) 708 WP_242746692.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  MP387_RS00205 (MP387_00205) - 37304..41029 (+) 3726 WP_242746695.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50138.04 Da        Isoelectric Point: 5.0513

>NTDB_id=668073 MP387_RS00195 WP_242746691.1 35022..36371(+) (comB) [Streptococcus oralis strain 1648]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLFVFLLGFSVFAEKEMSLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGELLVQYQQGAEAVQVEAYASQLEMLKDQKKQLEYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVTRVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEQ
GNFFKIEAETNLTSEQAEKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=668073 MP387_RS00195 WP_242746691.1 35022..36371(+) (comB) [Streptococcus oralis strain 1648]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGTTCGTGTTTTTACTAGGATTTTCAGTTTTTGCAGAGAAGGAGATGAGTTTGTCTACCAGAGCAACTGTCG
AACCTAGTCGGATTATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAATTATCTGGAAGAAAACAAGTTG
GTCAAGCAGGGGGAACTACTCGTTCAGTACCAACAAGGGGCGGAGGCTGTCCAGGTCGAAGCATACGCCAGCCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGAATATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAAGCAG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGAAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCCTCGCAGAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGTCAAACAGAGGATAA
AATCCGAGACTACAAAACAGCTAAGTCAGCAATTGAAAAGGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ACCAGACCTATAAAAATCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTCTAGCTACGTATCGTGTACAGTATGCGGGTTCTGGAGCTCAACAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCACTCAAATCTCAGCACTTAGTCAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAGGGAGGTCTCCTCGATAAGGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACCATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCCCTGGAAAAAGA
AGGGAAAACTAAACTCACAGCCTATCTCAGTTCAAAGGATGTTACTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAGACTGAACAA
GGAAATTTCTTTAAAATTGAAGCGGAGACTAATTTAACTTCAGAGCAGGCTGAAAAACTTCGTTATGGTTTAGAAGGCCG
CCTACAGATGATTACAGGAAAGAAAAGCTACCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.598

99.777

0.844
  comB Streptococcus pneumoniae Rx1

83.259

99.777

0.831
  comB Streptococcus pneumoniae D39

83.259

99.777

0.831
  comB Streptococcus pneumoniae R6

83.259

99.777

0.831
  comB Streptococcus pneumoniae TIGR4

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.812

99.777

0.826
  comB Streptococcus gordonii str. Challis substr. CH1

55.752

100

0.561

Multiple sequence alignment