Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   MP387_RS00190 Genome accession   NZ_CP094226
Coordinates   32856..35009 (+) Length   717 a.a.
NCBI ID   WP_242746689.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 27856..40009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS00155 (MP387_00155) - 28476..29645 (+) 1170 WP_242746687.1 pyridoxal phosphate-dependent aminotransferase -
  MP387_RS00160 (MP387_00160) recO 29642..30412 (+) 771 WP_125826015.1 DNA repair protein RecO -
  MP387_RS00165 (MP387_00165) plsX 30409..31401 (+) 993 WP_227232162.1 phosphate acyltransferase PlsX -
  MP387_RS00170 (MP387_00170) - 31407..31643 (+) 237 WP_000136435.1 acyl carrier protein -
  MP387_RS00175 (MP387_00175) - 31958..32134 (+) 177 WP_000180837.1 hypothetical protein -
  MP387_RS00180 (MP387_00180) - 32147..32338 (+) 192 WP_083321223.1 bacteriocin immunity protein -
  MP387_RS00185 (MP387_00185) - 32367..32537 (+) 171 WP_070837635.1 H354_08695 family bacteriocin-like peptide -
  MP387_RS00190 (MP387_00190) comA 32856..35009 (+) 2154 WP_242746689.1 peptide cleavage/export ABC transporter ComA Regulator
  MP387_RS00195 (MP387_00195) comB 35022..36371 (+) 1350 WP_242746691.1 competence pheromone export protein ComB Regulator
  MP387_RS00200 (MP387_00200) purC 36540..37247 (+) 708 WP_242746692.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80498.88 Da        Isoelectric Point: 7.3722

>NTDB_id=668072 MP387_RS00190 WP_242746689.1 32856..35009(+) (comA) [Streptococcus oralis strain 1648]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSIFMAPSPGYKPHKEKKQGLLSFLPI
LFKQRGLVTNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLEQGKIIEEGKHADLLAQDGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=668072 MP387_RS00190 WP_242746689.1 32856..35009(+) (comA) [Streptococcus oralis strain 1648]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGGTCTTTGG
CTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTAGCCAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGGTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATCTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGAAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGTTTTGCGCAAGAGTGGACAGGGG
TCAGTATTTTTATGGCGCCATCTCCGGGCTATAAACCTCATAAGGAGAAGAAACAGGGTCTCCTATCCTTCTTGCCGATT
TTATTCAAACAGCGTGGCTTAGTTACCAATATCGTCCTAGCGACACTCTTGGTAACCTTGATCAATATCGTGGGCTCCTA
CTATCTTCAGTCCATCATTGATAGTTACGTGCCAGATCAGATGCGCTCGACGCTGGGTATTATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAGATTTTGTCCTACGCGCAGGAATATCTCCTACTAATCCTTGGGCAGCGCTTGTCCATCGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCGATGTCCTTTTTCGCGACACGCAGGACAGGAGAAATCGTATC
TCGTTTTACAGATGCCAACAGTATCATCGATGCGTTGGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTGGTCTTGTTTTCACAAAATATGACACTCTTTTTCATTAGTCTGCTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGATACCATGGAAGCTAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCACGCTATCAAAAGATTGATAAGGAAT
TTGTGGCTTATCTGAAAAAATCCTTTACCTACAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGTTGGGAGCTATTCTTGTCATGGATGGGAAAATGAGTTTGGGTCAGCTGATTACTTA
TAACACCCTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGCATGATG
AAAGGGGATATGACCTTTAAACAGGTTCACTACAAGTATGGCTATGGTCGTGACGTCTTGTCGGATATCAATTTAACCAT
TCCGCAAGGGTCTAAGATGGCTTTTGTGGGGATTTCGGGGTCAGGAAAGACCACCTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTATATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
TCAAGAGGATATCTTACGGGCAGTCGAATTGGCCGAGATTCGAGAGGATATCGAGCGCATGCCACTGAATTACCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCAGGTGGACAACGTCAGCGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATCTTGGACGAGGCGACCAGCAGTCTGGATATTTTGACAGAGAAGCGGATTGTTGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATCGCCCACCGCTTGACCATCGCTGAGCGGACAGAGAAGGTTGTTGTTTTGGAACAGGGCA
AGATTATCGAAGAAGGAAAGCATGCAGACTTGCTTGCACAGGATGGATTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

94.421

100

0.944
  comA Streptococcus pneumoniae Rx1

94.282

100

0.943
  comA Streptococcus pneumoniae D39

94.282

100

0.943
  comA Streptococcus pneumoniae R6

94.282

100

0.943
  comA Streptococcus mitis SK321

94.142

100

0.941
  comA Streptococcus pneumoniae TIGR4

93.863

100

0.939
  comA Streptococcus gordonii str. Challis substr. CH1

80.335

100

0.803
  comA/nlmT Streptococcus mutans UA159

64.435

100

0.644

Multiple sequence alignment