Detailed information NTG0066554

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SCSC_RS02725
• Genome accession: NZ_AP014647
• Coordinates: 538849..540999 (+)
• Length: 716 a.a.
• NCBI ID: WP_006270130.1
• Uniprot ID: A0AAD2SW74
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 533849..545999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS02695 (SCSC_0555)	pyrH	533874..534614 (+)	741	WP_003069937.1	UMP kinase	-
SCSC_RS02700 (SCSC_0556)	frr	534618..535175 (+)	558	WP_003069936.1	ribosome recycling factor	-
SCSC_RS02705 (SCSC_0557)	cvfB	535288..536142 (+)	855	WP_006270135.1	RNA-binding virulence regulatory protein CvfB	-
SCSC_RS02710 (SCSC_0558)	holA	536223..537260 (+)	1038	WP_006270145.1	DNA polymerase III subunit delta	-
SCSC_RS02715 (SCSC_0559)	-	537330..537935 (+)	606	WP_006270121.1	superoxide dismutase	-
SCSC_RS02720 (SCSC_0560)	-	537991..538365 (-)	375	WP_006270124.1	hypothetical protein	-
SCSC_RS02725 (SCSC_0561)	comA/nlmT	538849..540999 (+)	2151	WP_006270130.1	peptide cleavage/export ABC transporter	Regulator
SCSC_RS02730 (SCSC_0562)	-	541010..542371 (+)	1362	WP_006270117.1	bacteriocin secretion accessory protein	-
SCSC_RS02735 (SCSC_0563)	-	542465..542614 (+)	150	WP_003025431.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SCSC_RS02740	-	542659..543480 (-)	822	WP_232565280.1	GHKL domain-containing protein	-
SCSC_RS02745 (SCSC_0565)	comE/blpR	543971..544717 (-)	747	WP_006270174.1	response regulator transcription factor	Regulator
SCSC_RS02750 (SCSC_0566)	-	544886..545599 (-)	714	WP_006270152.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80484.12 Da
• Isoelectric Point: 9.1745

>NTDB_id=66554 SCSC_RS02725 WP_006270130.1 538849..540999(+) (comA/nlmT) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYMVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLIEKGFLT
GDITFHNVSYKYGFGRDTLSDINLTIKIGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=66554 SCSC_RS02725 WP_006270130.1 538849..540999(+) (comA/nlmT) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTGGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCACAAGAAATAGGCTTTGAGACACGACCGATTCAAGGGGATATGTCCTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACATATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATATGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCTATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACTCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAATCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTATAGAGAAAGGTTTCTTGACT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AATAGGAGATAAGGTGAGCTTAGTCGGTATCAGTGGTTCGGGAAAGACAACGCTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGATCTTAAAATGATTGATAAGAAAACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAACCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGCTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAAGTGATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (499-648)

• Peptidase C39 family (Peptidase_C39) (6-141)

• ABC transporter transmembrane region (ABC_membrane) (168-437)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.214	99.022	0.715
comA	Streptococcus mitis NCTC 12261	66.62	99.581	0.663
comA	Streptococcus mitis SK321	66.48	99.581	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.199	99.581	0.659
comA	Streptococcus pneumoniae D39	65.919	99.581	0.656
comA	Streptococcus pneumoniae R6	65.919	99.581	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.581	0.656
comA	Streptococcus pneumoniae TIGR4	65.498	99.581	0.652