Detailed information NTG0066189

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SRT_RS08965
• Genome accession: NZ_AP014612
• Coordinates: 1843623..1845902 (-)
• Length: 759 a.a.
• NCBI ID: WP_128833841.1
• Uniprot ID: A0A1L7LLV3
• Organism: Streptococcus troglodytae strain TKU 31
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1838623..1850902

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SRT_RS08940 (SRT_18300)	trpD	1838967..1839971 (-)	1005	WP_128833838.1	anthranilate phosphoribosyltransferase	-
SRT_RS08945 (SRT_18310)	-	1840019..1840588 (-)	570	WP_128833839.1	aminodeoxychorismate/anthranilate synthase component II	-
SRT_RS08950 (SRT_18320)	trpE	1840585..1841940 (-)	1356	WP_128833840.1	anthranilate synthase component I	-
SRT_RS11175	-	1842379..1842510 (-)	132	WP_256376012.1	hypothetical protein	-
SRT_RS11395 (SRT_18340)	-	1842557..1842775 (-)	219	Protein_1755	Rgg/GadR/MutR family transcriptional regulator	-
SRT_RS08960 (SRT_18360)	-	1842699..1843609 (-)	911	Protein_1756	HlyD family efflux transporter periplasmic adaptor subunit	-
SRT_RS08965 (SRT_18370)	comA/nlmT	1843623..1845902 (-)	2280	WP_128833841.1	peptide cleavage/export ABC transporter	Regulator
SRT_RS10450 (SRT_18380)	-	1846183..1846326 (-)	144	WP_167373732.1	hypothetical protein	-
SRT_RS08980	-	1846753..1847183 (-)	431	Protein_1759	hypothetical protein	-
SRT_RS10365	-	1847208..1847354 (-)	147	WP_162604151.1	hypothetical protein	-
SRT_RS08985 (SRT_18400)	-	1847760..1848020 (-)	261	WP_128833843.1	hypothetical protein	-
SRT_RS08990	-	1848736..1848945 (-)	210	WP_128833844.1	hypothetical protein	-
SRT_RS11285 (SRT_18420)	-	1849417..1849551 (-)	135	Protein_1763	bacteriocin	-
SRT_RS09000 (SRT_18430)	-	1849978..1850688 (-)	711	WP_128833845.1	L-ribulose-5-phosphate 4-epimerase	-

Sequence

Protein

• Length: 759 a.a.
• Molecular weight: 84962.56 Da
• Isoelectric Point: 7.5967

>NTDB_id=66189 SRT_RS08965 WP_128833841.1 1843623..1845902(-) (comA/nlmT) [Streptococcus troglodytae strain TKU 31]
MEQVIYVVLIVIAVNILLEVIKRVTKRGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIAH
LRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYDDLTYPFIVHVIKGKRLQHYYVVYGSQNDQLIIGDPDPSV
KVTKMSKERFQSEWTGLAIFLAPQPSYKPHKGEKNGLSDFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEYI
PDQLISTLGMITIGLIITYIIQQIMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQIID
AVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMETI
KSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSNP
IENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLVG
ASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACEI
AEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAHR
LSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2280 bp

>NTDB_id=66189 SRT_RS08965 WP_128833841.1 1843623..1845902(-) (comA/nlmT) [Streptococcus troglodytae strain TKU 31]
ATGGAACAAGTTATTTATGTTGTTTTAATCGTCATAGCTGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACGAAAAG
AGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTGGTACCTC
AGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGTTCTAACTACTCTATTGCTCAT
CTGCGGGAACTTTCAAAGACTAACAAGCAAGGAACGACAGCTCTTGGCATCGTTGAAGCTGCTAAAAAGTTAGGTTTTGA
AACGCGCTCTATCAAGGCGGATATGACGCTTTTTGATTATGATGATTTGACCTATCCTTTTATCGTCCATGTGATTAAAG
GAAAACGACTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATGATCAGCTGATTATTGGAGATCCTGATCCTTCAGTT
AAGGTGACTAAGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGTCTTGCGATTTTTCTAGCTCCTCAGCCTAGTTA
TAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCCGATTTCTTCCCGCTGATCTTTAAGCAGAAAGCTTTGATGACTTATA
TTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTACATT
CCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGATTATGGCTTT
TGCAAAAGAATACCTCTTGGCCGTGCTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATTAAACATATTTTTA
CGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGGGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATTGAT
GCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTGATTTTGGTTGGCGGGGTTTTATTGGCGCAAAA
CAATAATCTTTTCTTTCTGACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTGAGA
AAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGACATCAATGGGATGGAAACCATT
AAATCACTTACAAGTGAGTCAGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAAGCT
GCACAAGTATAGTGCTATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATTCTCAATGTCGTCATTCTCTGGTATGGCT
CTCGCCTAGTGATGGATAATAAGATCTCAGTTGGTCAGCTTATCACTTTTAATGCTTTGCTGTCTTATTTCTCAAATCCG
ATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCTAGT
TGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAGAATCTTTCTT
ACAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGCCTAGTTGGA
GCCAGTGGTTCTGGTAAGACGACTTTGGCTAAACTGATTGTCAATTTTTACGAGCCTAACAAAGGGATTGTTCGGATTAA
TGGCAATGATTTGAAAGTTATTGATAAGACAGCTTTGCGACGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTTTTA
GTGGTTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCCTGTGAAATT
GCTGAAATCCGCTCGGACATTGAACAAATGCCTCAAGGTTATCAGACAGAGTTATCAGATGGTGCCGGCATTTCTGGCGG
TCAAAAACAGCGGATTGCTTTAGCTAGAGCCTTATTAACACAGGCACCAGTTTTGATTCTGGATGAAGCCACCAGTAGTC
TTGATATTCTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACGATAATTTTTGTTGCCCACCGC
TTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGAACT
TTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (543-692)

• Peptidase C39 family (Peptidase_C39) (49-185)

• ABC transporter transmembrane region (ABC_membrane) (211-480)

3D structure

• AlphaFold DB: A0A1L7LLV3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	98.684	100	0.988
comA	Streptococcus mitis NCTC 12261	65.969	94.466	0.623
comA	Streptococcus pneumoniae Rx1	65.411	94.466	0.618
comA	Streptococcus pneumoniae D39	65.411	94.466	0.618
comA	Streptococcus pneumoniae R6	65.411	94.466	0.618
comA	Streptococcus mitis SK321	65.132	94.466	0.615
comA	Streptococcus pneumoniae TIGR4	65.132	94.466	0.615
comA	Streptococcus gordonii str. Challis substr. CH1	64.714	94.466	0.611