Detailed information NTG0660955

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ML603_RS09855
• Genome accession: NZ_CP092887
• Coordinates: 1997373..1998593 (+)
• Length: 406 a.a.
• NCBI ID: WP_241067261.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain Karl
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1992373..2003593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ML603_RS09830 (ML603_09830)	-	1993315..1995891 (+)	2577	WP_241067260.1	YfhO family protein	-
ML603_RS09850 (ML603_09850)	rlmH	1996684..1997163 (-)	480	WP_129555129.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ML603_RS09855 (ML603_09855)	htrA	1997373..1998593 (+)	1221	WP_241067261.1	trypsin-like peptidase domain-containing protein	Regulator
ML603_RS09860 (ML603_09860)	spo0J	1998709..1999482 (+)	774	WP_241067262.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 406 a.a.
• Molecular weight: 42439.81 Da
• Isoelectric Point: 5.2146

>NTDB_id=660955 ML603_RS09855 WP_241067261.1 1997373..1998593(+) (htrA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MPSMKHILKSLGILLIGFLGGLLAIFTFNATQQSSSTSHTGSATTSKMVFNNTTDTTKAVKVVQNAVVSVINYQADPSSS
LSNPYTKLFGENQTRENKDADLAIFSEGSGVIYRKDGDSAYVVTNNHVIDGAKRIEILMADGTKVVGELVGADTYSDLAV
VKIASDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTEGIVSSLSRTVTLKNEDGETVSTNAIQTDAAINPGNSG
GPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSSDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQI
NIPTGVTGGIVVASVQDGMPASGKLAQYDVITEIDGKAVNSISDLQSNLYGHDINDTIKVTFYRGTTKKKADITLTKTTQ
DLTKKQ

Nucleotide

• Length: 1221 bp

>NTDB_id=660955 ML603_RS09855 WP_241067261.1 1997373..1998593(+) (htrA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGCCATCTATGAAACATATCTTAAAATCCTTAGGCATTTTACTCATTGGATTTTTAGGAGGATTGTTAGCAATTTTCAC
TTTTAATGCTACTCAACAGTCTTCCTCTACCTCACATACTGGTAGTGCGACGACGAGTAAGATGGTTTTTAATAATACTA
CTGACACAACAAAAGCGGTTAAAGTCGTTCAAAATGCAGTAGTATCAGTGATTAACTATCAAGCAGATCCTTCTTCATCT
CTTTCAAATCCCTACACAAAACTCTTTGGAGAAAATCAAACAAGAGAAAATAAAGATGCCGACTTAGCAATTTTTAGTGA
AGGTTCTGGTGTTATTTATCGAAAAGACGGTGATTCTGCATATGTTGTTACTAATAATCACGTCATTGACGGCGCAAAGC
GAATTGAAATTCTTATGGCAGACGGTACCAAAGTCGTAGGGGAGTTAGTTGGAGCTGATACTTACTCTGACTTAGCGGTT
GTTAAAATTGCCTCAGATAAAATTAAGACAGTTGCTGAATTTGCAGATTCTACTAAACTGAATGTCGGAGAAGTTGCTAT
CGCAATTGGTAGCCCATTAGGAACTCAGTATGCCAATTCTGTTACAGAAGGAATTGTTTCTAGTCTCAGTCGTACCGTCA
CCTTAAAAAATGAAGATGGGGAAACTGTTTCAACAAATGCCATTCAAACTGATGCTGCGATCAATCCCGGAAATTCTGGT
GGTCCGCTCATCAATATTGAAGGACAGGTTATTGGTATCAATTCAAGTAAAATTTCTTCTACCCCAACAGGAAGCAACGG
CAATAGTGGAGCGGTTGAAGGTATCGGTTTTGCTATTCCATCCAGTGATGTCATTAAAATCATTAAGCAATTAGAAACCA
ATGGTGAGGTTATCAGACCTGCCCTTGGAATCTCTATGGTTAATCTAAATGATTTATCAACGAATGCTCTCAGTCAAATT
AATATCCCTACTGGGGTGACGGGTGGTATTGTGGTCGCTTCTGTTCAAGATGGAATGCCAGCTAGTGGTAAACTTGCCCA
GTACGACGTTATTACTGAAATTGATGGTAAAGCCGTCAACTCAATCAGTGATCTTCAAAGCAACCTATACGGCCATGACA
TTAACGATACCATCAAGGTAACCTTTTATAGAGGGACAACCAAGAAAAAAGCAGATATTACCTTAACTAAAACAACCCAG
GATTTGACCAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (300-395)

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.945	99.015	0.603
htrA	Streptococcus mitis NCTC 12261	54.412	100	0.547
htrA	Streptococcus pneumoniae Rx1	54.412	100	0.547
htrA	Streptococcus pneumoniae TIGR4	54.412	100	0.547
htrA	Streptococcus pneumoniae D39	54.412	100	0.547
htrA	Streptococcus pneumoniae R6	54.412	100	0.547
htrA	Streptococcus gordonii str. Challis substr. CH1	54.95	99.507	0.547