Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ML603_RS04865 Genome accession   NZ_CP092887
Coordinates   988504..989178 (-) Length   224 a.a.
NCBI ID   WP_143927517.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 983504..994178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS04840 (ML603_04840) - 983689..984966 (-) 1278 WP_241067689.1 pyrimidine-nucleoside phosphorylase -
  ML603_RS04845 (ML603_04845) - 984953..985552 (-) 600 WP_280641428.1 class I SAM-dependent methyltransferase -
  ML603_RS04850 (ML603_04850) coaA 985821..986741 (+) 921 WP_129555680.1 type I pantothenate kinase -
  ML603_RS04855 (ML603_04855) rpsT 986795..987043 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  ML603_RS04860 (ML603_04860) ciaH 987201..988511 (-) 1311 WP_143927516.1 HAMP domain-containing sensor histidine kinase Regulator
  ML603_RS04865 (ML603_04865) ciaR 988504..989178 (-) 675 WP_143927517.1 response regulator transcription factor Regulator
  ML603_RS04870 (ML603_04870) - 989383..991920 (-) 2538 WP_241067691.1 M1 family metallopeptidase -
  ML603_RS04875 (ML603_04875) phoU 992121..992774 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  ML603_RS04880 (ML603_04880) pstB 992852..993610 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25629.59 Da        Isoelectric Point: 4.4123

>NTDB_id=660933 ML603_RS04865 WP_143927517.1 988504..989178(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLVFGNVVVDLGQKEVQVDGQPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVDRLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=660933 ML603_RS04865 WP_143927517.1 988504..989178(-) (ciaR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTTTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGCCTAGATGATAAGGGACATGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACGGGGAAATTCACGGATAAAAATCTAGTCTTTGGGAACGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCAGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGGTACAGATTTTGTGGATAGACTGCAGACATTGA
GAAGCGTGGGGTACATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae D39

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae R6

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.615

98.661

0.835
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

34.322

100

0.362