Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ML603_RS04860 Genome accession   NZ_CP092887
Coordinates   987201..988511 (-) Length   436 a.a.
NCBI ID   WP_143927516.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 982201..993511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS04830 (ML603_04830) - 982635..983024 (-) 390 WP_138125674.1 cytidine deaminase -
  ML603_RS04835 (ML603_04835) deoC 983011..983673 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  ML603_RS04840 (ML603_04840) - 983689..984966 (-) 1278 WP_241067689.1 pyrimidine-nucleoside phosphorylase -
  ML603_RS04845 (ML603_04845) - 984953..985552 (-) 600 WP_280641428.1 class I SAM-dependent methyltransferase -
  ML603_RS04850 (ML603_04850) coaA 985821..986741 (+) 921 WP_129555680.1 type I pantothenate kinase -
  ML603_RS04855 (ML603_04855) rpsT 986795..987043 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  ML603_RS04860 (ML603_04860) ciaH 987201..988511 (-) 1311 WP_143927516.1 HAMP domain-containing sensor histidine kinase Regulator
  ML603_RS04865 (ML603_04865) ciaR 988504..989178 (-) 675 WP_143927517.1 response regulator transcription factor Regulator
  ML603_RS04870 (ML603_04870) - 989383..991920 (-) 2538 WP_241067691.1 M1 family metallopeptidase -
  ML603_RS04875 (ML603_04875) phoU 992121..992774 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49938.49 Da        Isoelectric Point: 8.2375

>NTDB_id=660932 ML603_RS04860 WP_143927516.1 987201..988511(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLSLAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=660932 ML603_RS04860 WP_143927516.1 987201..988511(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATATACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGCAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGTACAATTTTGAATTCCTTTGATGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACTATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTAGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGACGATGGGATCAACCCTCAATGGACTGACTTGG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCAATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAATGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGTCCTTAGCTCAACAAATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAATCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

58.352

100

0.585
  ciaH Streptococcus pneumoniae Rx1

51.598

100

0.518
  ciaH Streptococcus pneumoniae D39

51.598

100

0.518
  ciaH Streptococcus pneumoniae R6

51.598

100

0.518
  ciaH Streptococcus pneumoniae TIGR4

51.598

100

0.518