Detailed information NTG0660897

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ML603_RS00335
• Genome accession: NZ_CP092887
• Coordinates: 52364..53275 (+)
• Length: 303 a.a.
• NCBI ID: WP_241067279.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain Karl
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 47364..58275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ML603_RS00315 (ML603_00315)	purD	47439..48701 (+)	1263	WP_241067275.1	phosphoribosylamine--glycine ligase	-
ML603_RS00320 (ML603_00320)	purE	49351..49839 (+)	489	WP_241067276.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
ML603_RS00325 (ML603_00325)	purK	49826..50920 (+)	1095	WP_241067277.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
ML603_RS00330 (ML603_00330)	purB	50930..52222 (+)	1293	WP_241067278.1	adenylosuccinate lyase	-
ML603_RS00335 (ML603_00335)	comR	52364..53275 (+)	912	WP_241067279.1	XRE family transcriptional regulator	Regulator
ML603_RS00340 (ML603_00340)	comS	53363..53461 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
ML603_RS00345 (ML603_00345)	ruvB	53495..54493 (+)	999	WP_241067281.1	Holliday junction branch migration DNA helicase RuvB	-
ML603_RS00350 (ML603_00350)	-	54628..55059 (+)	432	WP_241067283.1	low molecular weight protein-tyrosine-phosphatase	-
ML603_RS00355 (ML603_00355)	-	55088..55489 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
ML603_RS00360 (ML603_00360)	-	55486..57261 (+)	1776	WP_241067284.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35908.49 Da
• Isoelectric Point: 4.6217

>NTDB_id=660897 ML603_RS00335 WP_241067279.1 52364..53275(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFINDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQQEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=660897 ML603_RS00335 WP_241067279.1 52364..53275(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGTTAGAGCATTTTGGTGAAAAAGTTAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGCCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTACTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCCAACTTTATAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTATCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAC
AAGAATGGGATAAGGATATTCATCCATCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.721	99.34	0.832
comR	Streptococcus pyogenes MGAS8232	56.291	99.67	0.561
comR	Streptococcus mutans UA159	45.819	98.68	0.452
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363