Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   SMUNUM_RS07040 Genome accession   NZ_AP014571
Coordinates   1455192..1455899 (-) Length   235 a.a.
NCBI ID   WP_002262930.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1450192..1460899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS07025 (SMNUM_1344) rnc 1452245..1452940 (-) 696 WP_002266141.1 ribonuclease III -
  SMUNUM_RS07030 (SMNUM_1345) vicX 1453047..1453850 (-) 804 WP_002264820.1 MBL fold metallo-hydrolase Regulator
  SMUNUM_RS07035 (SMNUM_1346) vicK 1453847..1455199 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUNUM_RS07040 (SMNUM_1347) vicR 1455192..1455899 (-) 708 WP_002262930.1 response regulator YycF Regulator
  SMUNUM_RS07045 (SMNUM_1348) - 1456252..1457034 (+) 783 WP_002266943.1 amino acid ABC transporter ATP-binding protein -
  SMUNUM_RS07050 (SMNUM_1349) - 1457031..1457843 (+) 813 WP_019805462.1 transporter substrate-binding domain-containing protein -
  SMUNUM_RS07055 (SMNUM_1350) - 1457861..1458565 (+) 705 WP_002264823.1 amino acid ABC transporter permease -
  SMUNUM_RS07060 (SMNUM_1351) - 1458580..1459230 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUNUM_RS07065 (SMNUM_1352) endA 1459298..1460179 (-) 882 WP_168747714.1 DNA/RNA non-specific endonuclease Machinery gene
  SMUNUM_RS07070 (SMNUM_1353) - 1460221..1460409 (-) 189 WP_002264826.1 DNA-directed RNA polymerase subunit beta -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26914.70 Da        Isoelectric Point: 4.8288

>NTDB_id=65984 SMUNUM_RS07040 WP_002262930.1 1455192..1455899(-) (vicR) [Streptococcus mutans LP13]
MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=65984 SMUNUM_RS07040 WP_002262930.1 1455192..1455899(-) (vicR) [Streptococcus mutans LP13]
ATGAAGAAAATTCTAATCGTTGACGATGAAAAACCAATTTCTGATATCATCAAGTTTAACTTGGCTAAGGAAGGTTATGA
CACGATTACAGCCTTTGATGGGCGTGAAGCATTAAGTAAATATGAAGAAGAAAATCCTGACTTGATTATATTGGACTTAA
TGTTACCAGAACTAGACGGTCTTGAAGTGGCTAAGGAAGTTAGAAAAAACAGCCATGTTCCAATTATTATGTTATCAGCT
AAAGACAGTGAGTTTGATAAGGTTATTGGTCTTGAAATTGGTGCTGATGATTATGTGACTAAACCTTTTTCTAATCGTGA
ATTACTGGCGCGTGTAAAAGCGCATCTTCGCCGTACTGAAAATATTGAATCCGCAGTGGCTGAGGAAAATGCTTCAGGTA
TACCTGAAATTATTATTGGGGACTTGCAAATCTTACCAGATGCTTTTGTTGCTAAAAAACGTGGAACAGAGGTAGAGTTA
ACTCACCGTGAGTTTGAGCTGTTGCATCACTTAGCGACACACACAGGTCAGGTGATGACGCGTGAACATTTACTTGAAAC
GGTTTGGGGCTATGATTATTTTGGAGATGTCCGTACTGTTGATGTTACTGTTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCAGAGTACATTTTGACGCGACGCGGTGTTGGTTATTACATGAAATCATATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.887

98.298

0.451

Multiple sequence alignment