Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SMUNUM_RS07035 Genome accession   NZ_AP014571
Coordinates   1453847..1455199 (-) Length   450 a.a.
NCBI ID   WP_002264821.1    Uniprot ID   A0AAX1K2Z0
Organism   Streptococcus mutans LP13     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1448847..1460199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS07025 (SMNUM_1344) rnc 1452245..1452940 (-) 696 WP_002266141.1 ribonuclease III -
  SMUNUM_RS07030 (SMNUM_1345) vicX 1453047..1453850 (-) 804 WP_002264820.1 MBL fold metallo-hydrolase Regulator
  SMUNUM_RS07035 (SMNUM_1346) vicK 1453847..1455199 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SMUNUM_RS07040 (SMNUM_1347) vicR 1455192..1455899 (-) 708 WP_002262930.1 response regulator YycF Regulator
  SMUNUM_RS07045 (SMNUM_1348) - 1456252..1457034 (+) 783 WP_002266943.1 amino acid ABC transporter ATP-binding protein -
  SMUNUM_RS07050 (SMNUM_1349) - 1457031..1457843 (+) 813 WP_019805462.1 transporter substrate-binding domain-containing protein -
  SMUNUM_RS07055 (SMNUM_1350) - 1457861..1458565 (+) 705 WP_002264823.1 amino acid ABC transporter permease -
  SMUNUM_RS07060 (SMNUM_1351) - 1458580..1459230 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  SMUNUM_RS07065 (SMNUM_1352) endA 1459298..1460179 (-) 882 WP_168747714.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51752.41 Da        Isoelectric Point: 4.4951

>NTDB_id=65983 SMUNUM_RS07035 WP_002264821.1 1453847..1455199(-) (vicK) [Streptococcus mutans LP13]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRRGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTVTMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=65983 SMUNUM_RS07035 WP_002264821.1 1453847..1455199(-) (vicK) [Streptococcus mutans LP13]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACTCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCCGCGGAAAGATTACCGTTATTAACGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCGGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGCTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATCTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTGTAACGATGCAGACAACAGATACACAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAACGATAATGATGCAATTGATGAATGGGAAGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

99.556

100

0.996
  micB Streptococcus pneumoniae Cp1015

67.599

95.333

0.644

Multiple sequence alignment