Detailed information NTG0065954

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SMUNUM_RS01425
• Genome accession: NZ_AP014571
• Coordinates: 272586..274868 (+)
• Length: 760 a.a.
• NCBI ID: WP_002271629.1
• Uniprot ID: -
• Organism: Streptococcus mutans LP13
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 267586..279868

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNUM_RS01385 (SMNUM_0235)	-	268473..268772 (+)	300	WP_042669255.1	hypothetical protein	-
SMUNUM_RS01390 (SMNUM_0236)	-	269053..269271 (+)	219	WP_168749651.1	Blp family class II bacteriocin	-
SMUNUM_RS01395 (SMNUM_0237)	-	269290..269697 (+)	408	WP_002270936.1	hypothetical protein	-
SMUNUM_RS01400 (SMNUM_0238)	-	269747..269923 (+)	177	WP_019312478.1	hypothetical protein	-
SMUNUM_RS01405	-	269964..270125 (+)	162	WP_162470319.1	hypothetical protein	-
SMUNUM_RS01410 (SMNUM_0240)	-	270597..270806 (+)	210	WP_002263944.1	hypothetical protein	-
SMUNUM_RS01415 (SMNUM_0241)	-	271045..271302 (+)	258	WP_025986744.1	hypothetical protein	-
SMUNUM_RS01420 (SMNUM_0242)	-	271981..272157 (+)	177	WP_168747632.1	hypothetical protein	-
SMUNUM_RS01425 (SMNUM_0243)	comA/nlmT	272586..274868 (+)	2283	WP_002271629.1	peptide cleavage/export ABC transporter	Regulator
SMUNUM_RS01430 (SMNUM_0244)	comB/nlmE	274882..275784 (+)	903	WP_002263524.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
SMUNUM_RS01435 (SMNUM_0245)	-	276157..277824 (+)	1668	WP_019805321.1	transcription antiterminator	-
SMUNUM_RS01440 (SMNUM_0246)	ulaG	278404..279495 (+)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85108.80 Da
• Isoelectric Point: 8.9003

>NTDB_id=65954 SMUNUM_RS01425 WP_002271629.1 272586..274868(+) (comA/nlmT) [Streptococcus mutans LP13]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRYISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=65954 SMUNUM_RS01425 WP_002271629.1 272586..274868(+) (comA/nlmT) [Streptococcus mutans LP13]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTATGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTGATTTTGGTTGGCGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAAGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGTGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGTATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAAGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

• ABC transporter (ABC_tran) (544-693)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.737	100	0.997
comA	Streptococcus mitis NCTC 12261	65.551	94.342	0.618
comA	Streptococcus pneumoniae Rx1	64.993	94.342	0.613
comA	Streptococcus pneumoniae D39	64.993	94.342	0.613
comA	Streptococcus pneumoniae R6	64.993	94.342	0.613
comA	Streptococcus mitis SK321	64.854	94.342	0.612
comA	Streptococcus pneumoniae TIGR4	64.714	94.342	0.611
comA	Streptococcus gordonii str. Challis substr. CH1	64.575	94.342	0.609